Effect of Cilostazol on Carotid Atherosclerosis Estimated by 3D Ultrasound in Patients With Type 2 Diabetes

Effect of Cilostazol, a Phosphodiesterase 3 Inhibitor, on Carotid Atherosclerosis Estimated by 3D Ultrasound in Patients With Type 2 Diabetes

To investigate the effect of cilostazol compared with aspirin on carotid atherosclerosis in patients with type 2 diabetes mellitus

Inclusion Criteria:

• Age between 30 and 80 years
• Patients with type 2 diabetes on treatment (HbA1c 6.0-11.0%)
• Carotid plaque on 3D ultrasound

Exclusion Criteria:

• Acute bleeding or bleeding tendency
• Diagnosed with heart failure
• Suggestive of ischemia on ECG
• Uncontrolled hypertension
• Recently diagnosed with peptic ulcer disease
• Taking other antiplatelet agents
• Hypersensitivity to salicylic acid
• Aspirin induced asthma
• Severe kidney, liver, heart disease