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Co-ingesting protein with carbohydrate is an effective way to improve postprandial glucose handling. The investigators have isolated and identified a bioactive protein extracted from seaweed. The investigators aim to explore how varying doses of seaweed protein influence postprandial glycaemia and insulinaemia in a healthy population.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control | Placebo Comparator | 0.6g/kg body mass maltodextrin in solution. |
|
| Low protein | Experimental | 0.6g/kg body mass maltodextrin PLUS 0.075g/kg body mass protein from Biodulse, in solution |
|
| Medium protein | Experimental | 0.6g/kg body mass maltodextrin PLUS 0.15g/kg body mass protein from Biodulse, in solution |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Seaweed protein | Dietary Supplement | Novel protein extracted from seaweed |
|
| Measure | Description | Time Frame |
|---|---|---|
| Postprandial blood glucose area under the curve (AUC) | Integrated area under curve of blood glucose concentration (measured as mmol/L) over 120min | 120 min |
| Measure | Description | Time Frame |
|---|---|---|
| Timecourse of blood glucose concentration | Timecourse of blood glucose concentration (measured as mmol/L) | 0, 15, 30, 45, 60, 90, 120 min |
| Postprandial serum insulin area under the curve (AUC) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Brian Carson, PhD | University of Limerick | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Limerick | Limerick | V94 T9PX | Ireland |
No individual data will be shared with researchers outside of those named on the institutional ethics application form.
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A three arm, acute randomised, double blind crossover design feeding study will be used to establish the impact and dose response to co-ingestion of BioDulse (a protein hydrolysate from Irish seaweed) with maltodextrin on postprandial blood glucose and insulin concentrations.
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Integrated area under curve of blood glucose concentration (measured as mU/L) over 120min
| 120 min |
| Postprandial serum insulin concentration | Timecourse of serum insulin concentration (measured as mU/L) | 0, 15, 30, 45, 60, 90, 120 min |