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In this study, it was aimed to compare the effects of pressure-controlled volume-guaranteed ventilation (PCV-VG) and volume-controlled ventilation (VCV) on lung dynamics and hemodynamics in patients undergoing vertebral surgery in the prone position.
The VCV (volume controlled ventilation) mode is the mode commonly used in general anesthesia practice. In VCV mode, the parameters under control are tidal volume and respiratory rate. In VCV mode, airway pressure changes depending on resistance and compliance. There is a risk of increased airway pressures in this mode.
In PCV-VG (pressure controlled volume guaranteed ventilation) mode, the parameters under control are the peak airway inspiratory pressure and the I/E ratio. It has been shown that peak airway pressures decrease and partial oxygen pressure increase due to decreased inspiratory flow in this ventilation mode.
Both ventilation modes are frequently used in patients undergoing general anesthesia.
In this study, it was aimed to compare the effects of pressure-controlled volume-guaranteed ventilation (PCV-VG) and volume-controlled ventilation (VCV) on lung dynamics (pulmonary peak-plateau pressure, compliance, driving pressure, SpO2 and end-tidal carbon dioxide) and hemodynamics (mean arterial pressure and heart rate) in patients undergoing vertebral surgery in the prone position.
In the study, patients will be randomized and divided into 2 groups after obtaining informed consent forms. If a mode change is required during the surgery, that patient will be excluded from the study.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group PCV-VG | In this group, pressure-controlled volume guaranteed ventilation (PCV- VG) was applied in patients undergoing vertebral surgery in the prone position. |
| |
| Group VCV | In this group, volume-controlled ventilation (VCV) was applied in patients undergoing vertebral surgery in the prone position. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| The mechanical ventilation mode | Device | Changing the mechanical ventilation mode |
|
| Measure | Description | Time Frame |
|---|---|---|
| Comparison of the effects of pressure controlled volume guaranteed ventilation and volume controlled ventilation on lung compliance | Comparison of the effects of pressure controlled volume guaranteed ventilation (PCV-VG) and volume controlled ventilation (VCV) on lung compliance (ml/cmH20) in patients undergoing vertebral surgery in a prone position | 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Comparison of the effects of pressure controlled volume guaranteed ventilation and volume controlled ventilation on heart rate | Comparison of the effects of pressure controlled volume guaranteed ventilation (PCV-VG) and volume controlled ventilation (VCV) on heart beats per minute (bpm) in patients undergoing vertebral surgery in a prone position | 3 months |
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Inclusion Criteria:
Exclusion Criteria:
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Patients undergoing vertebral surgery in the prone position.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Derya A Yurtlu, M.D. | Contact | +0905058764132 | darslanyurtlu@yahoo.com |
| Name | Affiliation | Role |
|---|---|---|
| Derya A Yurtlu, M.D. | Izmir Atatürk Training and Reseach Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| KCU Izmir Atatürk Training and Research Hospital | Recruiting | Izmir | 35150 | Turkey (Türkiye) |
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| Comparison of the effects of pressure-controlled volume guaranteed ventilation and volume-controlled ventilation on mean arterial pressure | Comparison of the effects of pressure controlled volume guaranteed ventilation (PCV-VG) and volume controlled ventilation (VCV) on mean arterial pressure (mmHg) in patients undergoing vertebral surgery in a prone position | 3 months |