Bone Marrow Aspirate Concentrate in Treating Mandibular Cystic Defects

The Effect of Bone Marrow Aspirate Concentrate in the Treatment of Mandibular Cystic Defects (Randomized Clinical Trial)

Mandibular cystic defect healing is a complex process. Various methods have been developed to shorten the bone regeneration time and improve its quality. Autogenous grafting is the gold standard for filling cystic defects due to the osteogenesis property provided by the viable cells but is related to donor site morbidity. Allografts and Xenografts are used for the same purpose. However, the increased cost is their main disadvantage. Bone marrow aspirate concentrate is now used to enhance the healing and regeneration process in many areas of the body with no morbidity and low cost.

Inclusion Criteria:

• Patients suffering from mandibular cystic defect.
• Cystic defect width of 4-8 cm that requires removal under general anesthesia.

Exclusion Criteria:

• Medically compromised patients contradicting operation.
• Previously enucleated lesions.
• Previous surgery, tumor, infection to the pelvis affecting the anterior iliac crest.
• Infected Cysts