Efficacy of Nanoparticle-incorporated Bonding Agent on Post-restorative Sensitivity

Clinical Efficacy of a Novel Titania Nanoparticle-Reinforced Bonding Agent in Reducing Post-Restorative Sensitivity: A Randomized Clinical Trial

Type of study: Randomized Clinical trial To compare post-restorative sensitivity between titania nanoparticle reinforced bonding agent and bonding agent without nanoparticles in posterior composite restorations.

Participants aged 18 years and above with Class-I and Class-II Carious lesions are allocated in two groups. Group A will undergo composite restoration with Nanoparticles incorporated in bonding agent. Group B will undergo restoration without nanoparticles in bonding agent.

In this study Novel titania nanoparticle reinforced bonding agent will be evaluated for post-restorative sensitivity in composite restorations. Participants following the Inclusion criteria will be allocated in this study by Consecutive non-random sampling technique. Participants will be divided into two groups A and B. After rubber dam isolation, carious lesion will be excavated. In group A, titania nanoparticle reinforced bonding agent will be used for restorative treatment while in group B, Bonding agent without nanoparticles will be used. Post-restorative sensitivity record will be taken at 24 hours, after one week and after one month. Sensitivity will be assessed using Visual analog scale (VAS) mean score.

Inclusion Criteria:

• Participants with good general health
• Selected teeth should be vital and periodontally healthy
• Class-I and II with minimal cavity depth of 3mm, not exceeding 5mm
• Defective previous restorations in need of replacement (secondary caries/fractures)
• Selected teeth should be in occlusion with natural or prosthetic antagonist and adjacent teeth

Exclusion Criteria:

• Patients with Temporomandibular disorders
• Extremely poor oral hygiene status
• Teeth with very deep carious lesions
• Teeth with periapical or periodontal pathology
• Patients taking anti-inflammatory, analgesics or psychotropic drugs
• History of spontaneous pain
• Previously root canal treated teeth