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Randomized Clinical trial to compare the reduction in dentin hypersensitivity after incorporating biogenically fabricated titania nanoparticles enriched Mouth Wash and Conventional Mouth Wash.Participants ranging between 20-50 years were allocated in two groups. Group A will use Conventional Mouth Wash without Nanoparticles. Group B will use titania nanoparticles enriched Mouth Wash. Both will use them for three months and then their VAS scoring will be checked.
In this study Novel biogenically fabricated titania nanoparticle reinforced Mouth Wash will be evaluated for dentine sensitivity . Participants following Inclusion criteria will be allocated in this study by Consecutive random sampling technique. Participants will be divided into two groups i.e Group-A and Group-B with dentin sensitivity of 30-80. Group A will be given Conventional Mouth Wash for three months and Group-B will be given titania nanoparticles enriched Mouth Wash for three months for the sensitivity. Sensitivity will be assessed using Visual analog scale (VAS) mean score after 1 month and then three months.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group-A: Conventional Mouth wash . | Experimental | Group A will receive conventional mouthwash for treatment of dentin hypersensitivity |
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| Group-B: Novel Titania nanoparticles Mouth wash | Experimental | Group B will receive novel Titania nano particles reinforced mouthwash for treatment of dentin hypersensitivity |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Group- A Conventional Sensed Mouth Wash | Procedure | In Group- A Conventional Sensed Mouth Wash will be used for treatment of Dentin hypersensitivity. Visual Analogue scoring system will be used to calculate the dentin hypersensitivity. |
| Measure | Description | Time Frame |
|---|---|---|
| Post mouth wash utilization Dentine Hypersensitivity | Evaluation of dentine hypersensitivity with Conventional Mouth Wash without titania nanoparticles and Novel Nps Mouth Wash with titania nanoparticles on human tooth dentin. Visual analog scale with scoring from 0 to 100 where Score 100 means worst outcomes. | 3 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Afsheen Mansoor, PhD | School of Dentistry, Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad. | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| School of Dentistry, Pakistan Institute of Medical Sciences | Islamabad | Punjab Province | 44080 | Pakistan |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31592280 | Result | Aboelenein AZ, Riad MI, Haridy MF. Effect of a Self-Etch Adhesive Containing Nanobioglass on Postoperative Sensitivity of Posterior Composite Restorations - A Randomized Trial. Open Access Maced J Med Sci. 2019 Jul 25;7(14):2313-2320. doi: 10.3889/oamjms.2019.585. eCollection 2019 Jul 30. |
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| ID | Term |
|---|---|
| D003807 | Dentin Sensitivity |
| ID | Term |
|---|---|
| D014076 | Tooth Diseases |
| D009057 | Stomatognathic Diseases |
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In this study, participants will be allocated in two groups by Consecutive random sampling technique
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This is a triple-blinded study in which the participant, care provider and outcome assessor will be masked
| Group-B Novel Titania nanoparticles enriched Mouth Wash | Procedure | In Group-B Novel Titania nanoparticles enriched Mouth wash will be used to treat the Dentin hypersensitivity. Visual Analogue scoring system will be used to calculate the dentin hypersensitivity. |