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This triple-blind, randomized clinical trial was conducted at the department of Operative dentistry. A total of 60 participants were recruited and were randomly distributed into two groups A and B. After informed consent, restorative treatment was performed. In group A, adhesive with nanoparticles was used for composite restoration while in group B, adhesive without nanoparticles was utilized. Post-operative sensitivity was recorded using VAS score.
Triple-blind, randomized trial, parallel group with an allocation ratio 1:1. A total of 60 participants were recruited from the outpatient department and were randomly distributed into two groups (n=30). After informed consent, restorative treatment was accomplished using an etch and rinse adhesive strategy. In group A , titanium dioxide nano-fortified adhesive was used while in group B, adhesive without nanoparticles was utilized for composite restoration. Post-operative sensitivity was evaluated at follow-up period: one day, one week, two weeks and one month. Visual Analogue scale score was used to record the sensitivity status at follow-up intervals.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group A (Nano-fortified Adhesive) | Experimental | Titanium dioxide nanoparticles incorporated in dentin adhesive |
|
| Group B (Adhesive without Nanoparticles) | Experimental | Adhesive without nanoparticles |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Group A(Nano-fortified Adhesive) | Procedure | Nano-fortified dentin adhesive |
|
| Measure | Description | Time Frame |
|---|---|---|
| Post-operative sensitivity | Post-operative sensitivity evaluated at follow-up periods: one day, one week, two weeks and one month using Visual Analogue Scale score with the score 0( none) and score 3( severe sensitivity) | One month |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Nehal Amir, BDS | Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| School of Dentistry, Shaheed Zulfiqar Ali Bhutto Medical University | Islamabad | Pakistan |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31592280 | Background | Aboelenein AZ, Riad MI, Haridy MF. Effect of a Self-Etch Adhesive Containing Nanobioglass on Postoperative Sensitivity of Posterior Composite Restorations - A Randomized Trial. Open Access Maced J Med Sci. 2019 Jul 25;7(14):2313-2320. doi: 10.3889/oamjms.2019.585. eCollection 2019 Jul 30. | |
| 39267015 | Derived |
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| ID | Term |
|---|---|
| D003731 | Dental Caries |
| D003807 | Dentin Sensitivity |
| ID | Term |
|---|---|
| D017001 | Tooth Demineralization |
| D014076 | Tooth Diseases |
| D009057 | Stomatognathic Diseases |
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| ID | Term |
|---|---|
| D053758 | Nanoparticles |
| ID | Term |
|---|---|
| D049329 | Nanostructures |
| D008420 | Manufactured Materials |
| D013676 | Technology, Industry, and Agriculture |
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| Group B(Adhesive without nanoparticles) | Procedure | Conventional adhesives without nanoparticles |
|
| Amir N, Mansoor A, Eeman N, Ahmed MN, Mansoor E, Hussain K, Palma PJ. Postoperative sensitivity of composites using novel Bacillus subtilis nanofortified adhesives: a triple-blind study. BMC Oral Health. 2024 Sep 12;24(1):1077. doi: 10.1186/s12903-024-04825-2. |