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Thirty healthy patients will be selected from the outpatient clinic of the Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Mansoura University, to be included in this study with non-restorable posterior teeth.Patients will be selected according to the following criteria: 1) having a non-restorable posterior tooth. 2) being healthy, with no systemic diseases that might contraindicate receiving a dental implant. 3) having good oral hygiene. 4) aged between 18 to 45 years old. 5) having sufficient alveolar bone volume and height at the future implant site.Patients were classified into three groups:
All patients will be evaluated clinically and radiographically during a follow up period of 4 months, where the following criteria will be evaluated:
A- Clinical evaluation:
B- Radiographic evaluation:
C- Histological evaluation:
- Bone samples will be collected with trephine bur before implant placement, then fixed in 10% neutral buffered formalin for 24 hours, then transferred to 14% neutral buffered Ethylenediaminetetraacetic acid (EDTA) for decalcification 13. After confirming adequate decalcification, the specimens will be processed and embedded in paraffin blocks in the Pathology department, faculty of Medicine, Mansoura university for histological assessment, then stained with haematoxylin and eosin (H&E) as a routine stain to evaluate the quality of newly formed bone.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| control group | No Intervention | ten extraction sockets left for normal healing (blood clot). | |
| group 2 | Experimental | ten extraction sockets filled with Alloplast bone grafting material (EthOss, Ethoss Regeneration Ltd, Silsden, UK). |
|
| group 3 | Experimental | ten extraction sockets filled with Allograft bone grafting material. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Alloplast bone grafting material (EthOss, Ethoss Regeneration Ltd, Silsden, UK). | Other | After tooth extraction, the tooth socket will begrafted with Alloplast grafting material |
|
| Measure | Description | Time Frame |
|---|---|---|
| Bone density measurement | CBCT will be used to assess bone density categories and HU | 4 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Heba Elsheikh | Al Mansurah | 002 | Egypt |
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| Allograft bone grafting material. | Other | After tooth extraction, the tooth socket will be grafted with allograft grafting material |
|