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Among the objective non-invasive audiological explorations the distorsion products of otoacoustic emissions (DPOAE) allow to quickly assess the function of the cochlear outer hair cells (without the active participation of the subject). This technique is used in newborn screening. While humans are able to perceive sounds in a frequency range of 20Hz to 20kHz, routine clinical audiological assessment is only concerned with frequencies between 1-4kHz.
This obscures the importance of high frequencies (HF) which can be easily assessed by DPOAEs. In young children, the perception of these high frequencies could also play an important role in language acquisition.
The main objective of this study is to evaluate the relationship between subtle high-frequency hearing impairment, as assessed by the DPOAE (non-invasive, rapid and simple audiological test), and language delay or difficulties in a pre-, peri- and school-age pediatric population.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Case group (children with language disorder) | Experimental | Hearing diagnostic test |
|
| controle group (children without language disorder) | Other | Hearing diagnostic test |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| acoustic otoemisions | Diagnostic Test | TOAE and DPOAE |
|
| Measure | Description | Time Frame |
|---|---|---|
| HF DPOAE measurement | at frequencies 4265, 4688, 5154, 5666, 6229, 6847, 7527, 8275, 9096 and 10000 Hz | Day 1 |
| Measure | Description | Time Frame |
|---|---|---|
| Presence or absence of HF DPOAE | assessed by tympanometry, categorisation of this categorisation of this into 3 classes A, B and C frequency will be defined by a signal to noise ratio > 6 dB. The absence of DPOAE for each frequency will be defined by a signal to noise ratio ≤ 6 dB. | Day 1 |
| Functional status of the middle ear |
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Inclusion Criteria for case (children with language disorder):
Inclusion Criteria for control (children without language disorder) :
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Lise Laclautre | Contact | 04 73 75 11 95 | promo_interne_drci@chu-clermontferrand.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU Clermont-Ferrand, UMR INSERM 1107 | Clermont-Ferrand | France |
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| ID | Term |
|---|---|
| D007805 | Language Development Disorders |
| ID | Term |
|---|---|
| D007806 | Language Disorders |
| D003147 | Communication Disorders |
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
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| ID | Term |
|---|---|
| D038781 | Otoscopy |
| D001299 | Audiometry |
| D000158 | Acoustic Impedance Tests |
| ID | Term |
|---|---|
| D003939 | Diagnostic Techniques, Otological |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D006320 | Hearing Tests |
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one group of cases (children with language disorder) one group of control (children without language disorder)
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| Otoscopy | Diagnostic Test | presence of earwax checked by video otoscop |
|
| Audiometry | Diagnostic Test | Hearing Threshold will be measured with the AD528 interacoustics |
|
| Tympanometry | Diagnostic Test | Tympanic mobility will be measyred with the Titan interacoustics |
|
assessed by tympanometry, categorisation of this categorisation of this into 3 classes A, B and C |
| Day 1 |
| Determination of the average hearing loss (baseline pure tone audiometry) | according to the BIAP, average of audiometric thresholds at 500Hz thresholds at 500Hz, 1kHz, 2kHz and 4kHz | Day 1 |
| Laterality of hearing loss at the DPOAE level with a classification into 3 groups | Not affected bilaterally affected, unilateral affected, bilateral affected; one side is considered to be affected if at least one of the at least one of the HF DPOAEs is ≤ 6 dB. | Day 1 |
| Severity and type of language impairment assessed by the EVALO/ EVALEO | assessment and scoring by speech and language therapists | day 1 |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |