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| ID | Type | Description | Link |
|---|---|---|---|
| ID-RCB | Other Identifier | 2013-A00626-39 |
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The ability to encode the speech signal is determined by ascending and descending auditory processing. Difficulties in processing these speech signals are well described at the behavioral level in a specific language disorder. However, little is known about the underlying pathophysiological mechanisms. The assumption is that we should observe a degradation of the signal provided by the ear in the deaf subject while in case of specific language impairment it would be a phonemic disorder (possibly linked to a processing disorder auditory). The two population groups should therefore have different abnormalities of their central auditory process - which could be modified by the target remediation for each group.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1: Normal hearing children without SLI, transversal group | No Intervention | Normal hearing children without Specific Language Impairment (SLI),Transversal group for test-retest measures | |
| 2: Normal hearing children without SLI, longitudinal group | No Intervention | Normal hearing children without Specific Language Impairment (SLI), longitudinal group without training | |
| 3: Normal hearing children with SLI, longitudinal group | Other | Normal hearing children with Specific Language Impairment (SLI), longitudinal group with training |
|
| 4: Normal hearing adults without SLI, transversal group | No Intervention | Normal hearing adults without Specific Language Impairment (SLI), transversal group for test-retest measures | |
| 5: Normal hearing adults without SLI, longitudinal group | No Intervention | Normal hearing adults without Specific Language Impairment (SLI), longitudinal group without hearing aids (HA) | |
| 6: Hearing Impaired candidates for HA, longitudinal group | Other |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| E-learning | Other | Management of auditory processing disorders with serious game (E-learning) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change from Baseline speech auditory brainstem and late responses (composite and objective measure) in response to syllables (behavioral measure) | Spectro-temporal analysis of speech auditory brainstem and late responses : The speech brainstem and cortical responses are simultaneously obtained in response of different selected syllables from a continuum (selected by using a phonemic identification test) which is presented throughout a behavioral categorical procedure | Arms 2 and 3: Baseline and 5 weeks / Arms 5 and 6: Baseline and 6 months / Arms 1 and 4: Baseline |
| Measure | Description | Time Frame |
|---|---|---|
| Change from Baseline medial olivocochlear system (MOCS) functioning measured using the contralateral suppressive effect of transient evoked otoacoustic emissions (composite measure) | Measurement of the contralateral suppressive effect of transient evoked otoacoustic emissions (expressed as Equivalent Attenuation) | Arms 2 and 3: Baseline and 5 weeks / Arms 5 and 6: Baseline and 6 months / Arms 1 and 4: Baseline |
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Inclusion Criteria:
For all subjects:
For the normal-hearing subjects
For the subjects without specific language impairment
For the children with specific language impairment
For the hearing impaired subjects
Exclusion Criteria:
For children
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sercive d'Audiologie et d'Exploration Orofaciales, Hôpital Edouard Herriot, Hospices Civils de Lyon | Lyon | 69003 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32247718 | Result | Reynard P, Veuillet E, Thai-Van H. Paradoxical and labile medial olivocochlear functioning as a potential marker of auditory processing disorder in a child with learning disabilities. Eur Ann Otorhinolaryngol Head Neck Dis. 2020 Sep;137(4):339-342. doi: 10.1016/j.anorl.2020.03.005. Epub 2020 Apr 1. | |
| 25329609 | Result |
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| ID | Term |
|---|---|
| D007806 | Language Disorders |
| D034381 | Hearing Loss |
| D004410 | Dyslexia |
| ID | Term |
|---|---|
| D003147 | Communication Disorders |
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
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Hearing Impaired adult candidates for hearing aids (HA), longitudinal group with hearing aids (HA) |
|
| Hearing aids fitting | Device | Symmetrical hearing loss which are fitted with binaural hearing aids for the first time |
|
| Change from Baseline dichotic skills measured using central auditory processing tests (composite measure) | Presentation of different speech material to both ears simultaneously | Arms 2 and 3: Baseline and 5 weeks / Arms 5 and 6: Baseline and 6 months / Arms 1 and 4: Baseline |
| Change from Baseline speech-noise listening skills measured using logatomes tests (composite measure) | Presentation of disyllabic words in presence of increasing noise levels | Arms 2 and 3: Baseline and 5 weeks / Arms 5 and 6: Baseline and 6 months / Arms 1 and 4: Baseline |
| Bellier L, Bouchet P, Jeanvoine A, Valentin O, Thai-Van H, Caclin A. Topographic recordings of auditory evoked potentials to speech: subcortical and cortical responses. Psychophysiology. 2015 Apr;52(4):594-9. doi: 10.1111/psyp.12369. Epub 2014 Oct 20. |
| 25828076 | Result | Bellier L, Veuillet E, Vesson JF, Bouchet P, Caclin A, Thai-Van H. Speech Auditory Brainstem Response through hearing aid stimulation. Hear Res. 2015 Jul;325:49-54. doi: 10.1016/j.heares.2015.03.004. Epub 2015 Mar 27. |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D006311 | Hearing Disorders |
| D004427 | Ear Diseases |
| D010038 | Otorhinolaryngologic Diseases |
| D012678 | Sensation Disorders |
| D000067559 | Specific Learning Disorder |
| D007859 | Learning Disabilities |
| D065886 | Neurodevelopmental Disorders |
| D001523 | Mental Disorders |