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The hypothesis of central auditory processing disorders has been advanced to explain the anomalies of the grapheme/phoneme combination in some dyslexia. These phonological disorders may be linked to abnormalities of the efferent (medial olivocochlear) system modulation and of cortical asymmetry. Indeed, the efferent system has an asymmetry in relation to handedness. Thus, in right-handed subject, it is predominant on the right side. In contrast, in the subject-handed dyslexic, the efferent system tends to be right-lateralized or non-lateralized. However, after an audio-visual training, normal lateralization can appear. This maturation of the efferent system lateralization during reading acquisition seems to have a particular profile in dyslexics with phonological disorder, especially if it is persistent. This finding allows to consider new prognostic evaluation and speech therapy rehabilitation in the dyslexic child.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Dyslexic children | Longitudinal follow-up without intervention |
| |
| Normal reading children | Longitudinal follow-up without intervention |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| no intervention | Other |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change of The Asymmetry Index of the efferent system at 2 years interval | The change of the Asymmetry Index of the efferent system The Asymmetry Index is the difference between the equivalent attenuation measured on the right ear and the left ear. Evoked otoacoustic emissions were recorded monaurally at five stimulus intensities ranging from 57 to 69 dB SPL in 3 dB steps, in random presentation order, with and without contralateral acoustic stimulation consisting of 30 dBSPL continuous broadband noise (speech-like noise) produced by an audiometer | Day 1 and then at least 2 years (± 4 weeks) |
| Measure | Description | Time Frame |
|---|---|---|
| Change in the level of reading skill | Behavioral measure | Day 1 and then at least 2 years (± 4 weeks) |
| Change in the percentage of correct answers obtained during a speech perception test in silence and noise. |
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Common inclusion criteria
For the normal reading children
For the dyslexic children
Exclusion Criteria
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For the dyslexic children: primary care clinic and speech therapists For the normal reading children : elementary schools of Lyon and Clermond-Ferrand and their suburbs
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre Hospitzlier Le Vinatier | Bron | 69500 | France | |||
| Service ORL CHU Montpied |
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| ID | Term |
|---|---|
| D004410 | Dyslexia |
| ID | Term |
|---|---|
| D007806 | Language Disorders |
| D003147 | Communication Disorders |
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
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Oral repetition of VCV
| Day 1 and then at least 2 years (± 4 weeks) |
| Change in percentage of correctly repeated stimuli which have been heard in both ears (binaural integration with divided attention) or in one indicated ear (binaural separation with selective attention) | Presentation of different speech material to both ears simultaneously | Day 1 and then at least 2 years (± 4 weeks) |
| Clermont-Ferrand |
| 63003 |
| France |
| Service d'Audiologie et Explorations Orofaciales Centre de Référence des Troubles des Apprentissages | Lyon | France |
| D009422 | Nervous System Diseases |
| D000067559 | Specific Learning Disorder |
| D007859 | Learning Disabilities |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D065886 | Neurodevelopmental Disorders |
| D001523 | Mental Disorders |