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| ID | Type | Description | Link |
|---|---|---|---|
| 2014-A00345-42 | Other Identifier | ANSM |
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This study aims at investigating new automatic fitting techniques for cochlear implant patients based on objective measures. For this reason, the evolution of these neurophysiological measures, expressing the encoding of pure tones and speech, will be characterized in cochlear implanted patients as a function of post-implantation time and will be compared to those of normal hearing subjects. Moreover, the effect of auditory training with new tools based on serious games will be assessed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| newly cochlear implanted adult patients | Experimental | longitudinal group |
|
| newly cochlear implanted children | Experimental | longitudinal group |
|
| cochlear implanted adult patients (CI>1 year) | Active Comparator | transversal group |
|
| normal hearing adult subjects | Active Comparator | transversal group |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Auditory steady-state response ASSR | Other | comparison of ASSR amplitudes in response to amplitude-modulated sounds delivered at different intensities |
|
| Measure | Description | Time Frame |
|---|---|---|
| Amplitude of auditory steady state responses ASSR | one year at least after CI activation | |
| Spectro-temporal analysis of speech-ABR | one year at least after CI activation | |
| Acoustic Change Complex ACC | Amplitudes and latencies of ACC | one year at least after CI activation |
| amplitudes and latencies of P1/N1/P2 complex and Mismatch Negativity MMN | one year at least after CI activation | |
| Evolution of amplitude of auditory steady state responses ASSR | Evolution of ASSR amplitudes as a function of time during the first year of CI activation in newly implanted patients | 1 month, 3 months, 6 months, 9 months and 12 months after CI activation |
| Evolution of spectro-temporal analysis of speech-ABR | Evolution of spectro-temporal analysis of speech-ABR as a function of time during the first year of CI activation in newly implanted patients | 1 month, 3 months, 6 months, 9 months and 12 months after CI activation |
| Acoustic Change Complex ACC | Evolution of amplitudes and latencies of ACC as a function of time during the first year of CI activation in newly implanted patients | 1 month, 3 months, 6 months, 9 months and 12 months after CI activation |
| amplitudes and latencies of P1/N1/P2 complex and Mismatch Negativity MMN |
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Inclusion Criteria:
For the cochlear implanted patients:
For the normal-hearing subjects:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospices Civils de Lyon - Hopital Edouard Herriot | Lyon | 69003 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28692981 | Result | Attina V, Mina F, Stahl P, Duroc Y, Veuillet E, Truy E, Thai-Van H. A New Method to Test the Efficiency of Cochlear Implant Artifacts Removal From Auditory Evoked Potentials. IEEE Trans Neural Syst Rehabil Eng. 2017 Dec;25(12):2453-2460. doi: 10.1109/TNSRE.2017.2723952. Epub 2017 Jul 6. |
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| ID | Term |
|---|---|
| D003638 | Deafness |
| ID | Term |
|---|---|
| D034381 | Hearing Loss |
| D006311 | Hearing Disorders |
| D004427 | Ear Diseases |
| D010038 | Otorhinolaryngologic Diseases |
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| Speech-ABR | Other |
|
|
| Acoustic Change Complex ACC | Other | comparison of ACC complex in response to changes within speech stimulation |
|
| P1-N1-P2 complex and Mismatch Negativity MMN | Other | comparison of amplitudes and latencies of P1-N1-P2 complex and MMN generated in response to the detection of changes in a series of auditory stimulation |
|
Evolution of amplitudes and latencies of P1N1P2 and MMN as a function of time during the first year of CI activation in newly implanted patients |
| 1 month, 3 months, 6 months, 9 months and 12 months after CI activation |
| D012678 |
| Sensation Disorders |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |