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Phthalate esters have been considered closely related with childhood obesity, but the existing studies revealed inconsistent results. This study was desigened to investigate the association between phthalate esters and childhood obesity in China.
The physical activity, dietary intake and the levels of urine phthalate metabolites of children were detected, and the associations between these 3 factors and childhood obesity were analyzed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| cases | obesity / overweight children | ||
| controls | normal weight children |
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| Measure | Description | Time Frame |
|---|---|---|
| the levels of urine phthalate metabolites | 9 phthalate metabolites (MMP, MEP, MnBP, MiBP, MEHP, MEOHP, MEHHP, MCEPP, MCMHP) in first morning urine sample of the participants were detected | 3 months |
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Inclusion Criteria:
Exclusion Criteria:
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Students aged 6-8 years from monitoring schools in Shenzhen, China.
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37532921 | Derived | Li D, Yao Y, Chen D, Wu Y, Liao Y, Zhou L. Phthalates, physical activity, and diet, which are the most strongly associated with obesity? A case-control study of Chinese children. Endocrine. 2023 Oct;82(1):69-77. doi: 10.1007/s12020-023-03465-w. Epub 2023 Aug 2. |
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| ID | Term |
|---|---|
| D063766 | Pediatric Obesity |
| ID | Term |
|---|---|
| D009765 | Obesity |
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
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urine sample
| D009750 |
| Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |