The purpose of this study is to train nurses from the VNS Health Visiting Nurse Service to deliver Meaning-Centered Psychotherapy for Palliative Care Patients (MCP-PC) to homebound people, and to evaluate how effective MCP-PC is for people with cancer.

Participant Inclusion Criteria:

Nurses (all phases):

• Per self-report, providing direct care services at VNS Health
• Per self-report, fluent in English**
• Per self-report, is age 18 or older

Patients (all phases):

• Per health record and/or self-report, is a patient in the VNS Health home health agency division (post-acute care)

• Per health record and/or self-report, is age 18 or older

• Per health record, has a cancer diagnosis and a rating of ≥ 2 on Symptom Control Scale

• Per health record and/or self-report, fluent in English**

• Has a score of ≥ 4 on Callahan cognitive screener

• Has a score of ≥ 4 on Distress Thermometer (N/A for Training Case Participants)

  • Language verification: For both nurses and patients, prior to enrollment, all will be asked the following two questions by a Clinical Research Coordinator (CRC) to verify

English fluency necessary for participation in the study:

1. How well do you speak English? (must respond "very well" or "well" when given the choices of Very well, Well, Not well, Not at all, Don't know, or Refused)
2. What is your preferred language for healthcare? (must respond English)

Participant Exclusion Criteria:

Nurses (all phases):

• Per self-report, planning to leave position at VNS Health in the next 6 months

Patients (all phases):

• Per health record and/or self-report, has a diagnosis of Alzheimer's, dementia, or other organic brain disorder and in the judgment of the PIs is unable to meaningfully participate.
• Per health record, has impaired decision-making capacity
• Per health record and/or self-report, is permanently placed in a nursing home
• Per health record and/or self-report, is currently receiving Hospice care

Both patients and homecare nurses will be recruited and enrolled as participants in the proposed study. All participants will be recruited from VNS Health Visiting Nurse Service

Memorial Sloan Kettering Cancer Center supports the international committee of medical journal editors (ICMJE) and the ethical obligation of responsible sharing of data from clinical trials. The protocol summary, a statistical summary, and informed consent form will be made available on clinicaltrials.gov when required as a condition of Federal awards, other agreements supporting the research and/or as otherwise required. Requests for deidentified individual participant data can be made beginning 12 months after publication and for up to 36 months post publication. Deidentified individual participant data reported in the manuscript will be shared under the terms of a Data Use Agreement and may only be used for approved proposals. Requests may be made to: crdatashare@mskcc.org.