Catheter-interventional Treatment of Pulmonary Embolism

A Randomized Trial for Catheter-interventional Treatment of Intermediate High Risk Pulmonary Embolism

Recent evidence supports the use of catheter-interventional techniques for the treatment of intermediate-high-risk pulmonary embolism. While there is evidence supporting the use of catheter-thrombectomy and alternatively local fibrinolysis, less is known on the combination of both approaches.

The investigators aim to assess the effects of a combined interventional local fibrinolysis and catheter-thrombectomy and to compare them with conventional treatment in a cohort of patients with intermediate-high-risk pulmonary embolism.

Inclusion Criteria:

• confirmed intermediate high-risk pulmonary embolism
• age >= 18 years

Exclusion Criteria:

• high-risk pulmonary embolism
• contraindications for catheter-based treatment
• known allergy to anticoagulant treatment or fibrinolytics
• pregnancy
• participation in other randomized trials
• patients under legal supervision or guardianship