Effect of Remimazolam on Motor Evoked Potential

Influence of Propofol and Remimazolam on Intraoperative Responses of Motor Evoked Potentials During Spine Surgery

This study was planned to investigate the degree of effect of remimazolam on MEP compared to propofol when monitoring the motion-inducing potential (MEP).

Inclusion Criteria:

• Aged 20-70
• Scheduled for elective spine surgery requiring monitoring of evoked potential
• ASA physical status 1-3

Exclusion Criteria:

• BMI ≥ 40
• Uncontrolled DM (HbA1c ≥ 9%)
• Contraindications to the study drug: known allergy or hypersensitivity
• Use of rate responsive cardiac pacemaker with bioelectrical impedence
• Diagnosed neuromuscular disorder
• Pre-existing motor weakness