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| ID | Type | Description | Link |
|---|---|---|---|
| 2022-501021-20-00 | Other Identifier | EU CT |
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Comparing percutaneous needle fasciotomy +/- corticosteroid injection for Dupuytren's contracture affecting metacarpophalangeal joints. A clinician-initiated, multicenter, randomized controlled trial.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Corticosteroid injection | Active Comparator | Percutaneous needle fasciotomy with corticosteroid injection |
|
| Saline injection | Placebo Comparator | Percutaneous needle fasciotomy with saline injection |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Percutaneous needle fasciotomy | Procedure | Percutaneous needle fasciotomy ad modum Lermusiaux and Debeyre |
|
| Measure | Description | Time Frame |
|---|---|---|
| Recurrence rate | Recurrence is defined as 20 degrees or more passive extension deficit in metacarpophalangeal joint from baseline | 2 years |
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Sufficient correction of metacarpophalangeal (MCP) joint during the PNF treatment, defined as <20° passive extension deficit (PED), is a prerequisite for inclusion.
Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Laura H Matthiesen, MS, PhD-student | Contact | 004561281917 | lather@rm.dk | |
| Jeppe Lange, MD, PhD | Contact | jepplang@rm.dk |
| Name | Affiliation | Role |
|---|---|---|
| Jeppe Lange, MD, PhD | Regionshospitalet Horsens | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Silkeborg Regional Hospital | Recruiting | Silkeborg | 8600 | Denmark |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39749555 | Derived | Matthiesen LH, Skov ST, Lange J. Adjuvant steroid to percutaneous needle fasciotomy for Dupuytren's contracture. An RCT study protocol. Dan Med J. 2024 Nov 12;71(12):A05240324. doi: 10.61409/A05240324. |
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| Corticosteroid injection | Drug | Depo-Medrol |
|
| Saline injection | Other | Isotonic saline |
|
| ID | Term |
|---|---|
| D004387 | Dupuytren Contracture |
| D003286 | Contracture |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
| D005350 | Fibroma |
| D018218 | Neoplasms, Fibrous Tissue |
| D009372 | Neoplasms, Connective Tissue |
| D018204 | Neoplasms, Connective and Soft Tissue |
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
| D003240 | Connective Tissue Diseases |
| ID | Term |
|---|---|
| D009135 | Muscular Diseases |
| D017437 | Skin and Connective Tissue Diseases |
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| ID | Term |
|---|---|
| D000305 | Adrenal Cortex Hormones |
| D012965 | Sodium Chloride |
| ID | Term |
|---|---|
| D006728 | Hormones |
| D006730 | Hormones, Hormone Substitutes, and Hormone Antagonists |
| D002712 | Chlorides |
| D006851 | Hydrochloric Acid |
| D017606 | Chlorine Compounds |
| D007287 | Inorganic Chemicals |
| D017670 | Sodium Compounds |
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