Injectable Collagenase and Percutaneous Needle Fasciotomy for Dupuytren's Contracture

Comparing Injectable Collagenase (CI) and Percutaneous Needle Fasciotomy (PNF) for Dupuytren's Contracture (DC) Affecting Proximal Interphalangeal Joints (PIP). A Randomised Controlled Trial

Comparing injectable collagenase and percutaneous needle fasciotomy for Dupuytren's contracture affecting proximal interphalangeal joints. An open label, medico-independent randomized controlled trial.

Inclusion Criteria:

• DC affecting PIP joint with Passive Extension Deficit (PED) more than 20 degrees
• Clearly defined strings

Exclusion Criteria:

• Allergies to used medication
• International Normalised Ratio more than 2.0
• Pregnancy and breastfeeding
• Previous treatment for DC in affected finger
• Former inclusion in the study with another string
• Activity in disease at time of study
• PED more than 20 degrees for Metacarpophalangeal or Distal Interphalangeal joint in affected digit