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Effect of Topical Application of Hyaluronic Acid on Stability of Immediate Loading Dental Implant in Posterior Maxilla
Patients were randomly divided into two groups:
Group I (Control group):
Ten implants were placed in posterior maxilla and immediately loaded.
Group II (Study group):
Ten implants were coated with HA before placement in posterior maxilla and immediately loaded.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| control | Active Comparator | Each implant was placed into the prepared implant site. |
|
| Hyaluronic acid | Experimental | Each implant was placed after topical application of HA on its surface |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Hyaluronic acid | Other | immediate placement of dental implant after topical application of hyaluronic acid on implant surface |
|
| Measure | Description | Time Frame |
|---|---|---|
| implant stability | using radiofrequency analysis | immediately after surgery |
| implant stability | using radiofrequency analysis | one month |
| implant stability | using radiofrequency analysis | three months |
| implant stability | using radiofrequency analysis | six months |
| bone density | bone density around the implant is measured in cone beam computed tomography | three months |
| Measure | Description | Time Frame |
|---|---|---|
| propping depth | The distance between the gingival margin and the base of the pocket | six months |
| bleeding inex | Modified sulcus bleeding index |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Merna Elhadidi | Al Mansurah | Egypt |
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| ID | Term |
|---|---|
| D000848 | Anodontia |
| ID | Term |
|---|---|
| D014071 | Tooth Abnormalities |
| D018640 | Stomatognathic System Abnormalities |
| D009057 | Stomatognathic Diseases |
| D014076 | Tooth Diseases |
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| ID | Term |
|---|---|
| D006820 | Hyaluronic Acid |
| ID | Term |
|---|---|
| D006025 | Glycosaminoglycans |
| D011134 | Polysaccharides |
| D002241 | Carbohydrates |
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Twenty implants were inserted in patients seeking for replacement of missed single or multiple posterior maxillary teeth. Patients were divided randomly into two groups. In the control group, ten implants were placed and immediately loaded. While in the study group, ten implants were coated with hyaluronic acid (HA) immediately before placement and immediately loaded. All patients were clinically evaluated at implant placement time, one, three and six months after loading regarding implant stability. Peri-implant pocket depth and modified sulcus bleeding index were evaluated clinically at six months in all patients. Bone density was evaluated radiographically after three months. All clinical and radiographic data were subjected to statistical analysis.
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| conventional implant placement | Other | immediate placement of dental implant without application of hyaluronic acid on implant surface |
|
| six months |
| D000013 | Congenital Abnormalities |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |