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The concept of immediate implant placement at the time of tooth extraction was first introduced by Schulte et al. on animal studies. Since then, many follow-up studies examining different variables have supported the concept of immediate implant placement. pioneered a major contribution to immediate implant placement in human studies which recommended the insertion of an implant into a fresh extraction socket.
They advocated immediate implant placement primarily to reduce the number of surgical interventions needed to perform an implant-supported rehabilitation and shorten the treatment time.
Placement of implants immediately into extraction sites allow the surgeon to idealize the position of the implant appropriately with a better rehabilitation of the normal contour to the facial aspect of the final restoration.
Immediate implant placement in fresh extraction sockets was reported to reduce alveolar bone resorption. Better esthetic outcomes were achieved including the prosthetic crown length in harmony with the adjacent teeth, natural scalloping and easier distinct papillae to achieve and maximum soft tissue support.
Hyaluronic acid is a glycosaminoglycan, this unique molecule is implicated In a variety of biological functions including structural integrity, and the regulation of embryologic development. It is described as a natural organic substance, with physiological therapy activity, main component of the extracellular matrix of many tissues such as the skin, synovial joints and periodontal tissues .
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| implant with hyaluronic melatonin vit c | Experimental | implant placement with topical application of hyaluronic and melatonin and systemic administration of vitamin C |
|
| immediate implant | Active Comparator | immediate implant placement alone without melatonin or hyauronic acid nor vitamin c |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| immediate implant placement with melatonin hyaluronic acid vit C | Procedure | immediate implant placement with melatonin and hyaluronic acid and systemic administration vitamin C |
|
| Measure | Description | Time Frame |
|---|---|---|
| implant stability | implant stability by ostell | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| soft tissue healing | soft tissue healing by likert scale (0 indicate complete soft tissue Closure (no line of fibrin) , 1 indicate complete closure (thin line of fibrin) , 2 indcate complete closure (fibrin) , 3 indicate in complete closure (dehiscence ) , 4 indicate incomplete closure (necrosis) | 6 months |
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Inclusion Criteria:
Exclusion Criteria:
1. Smokers. 2. Systemic disease that may affect the final outcome of the surgical procedure.
3. No or poor patient's compliance. 4. Patients with psychological problems. 5. Pathology at the site of intervention. 6. Pregnant patients. 7. Patients refuse to sign an informed consent.
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| ahmed Nasser, Msc | Contact | 00201094959526 | ahmedelsawi8787@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Mona darhous, PHD | Cairo University | Study Chair |
| Mona shoieb, PHD | Cairo University | Study Chair |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24928668 | Background | Lee JH, Kim J, Baek HR, Lee KM, Seo JH, Lee HK, Lee AY, Zheng GB, Chang BS, Lee CK. Fabrication of an rhBMP-2 loaded porous beta-TCP microsphere-hyaluronic acid-based powder gel composite and evaluation of implant osseointegration. J Mater Sci Mater Med. 2014 Sep;25(9):2141-51. doi: 10.1007/s10856-014-5250-0. Epub 2014 Jun 14. | |
| 26103559 |
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i will check with my study chair
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it is randomized clinical trial
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single blinded
|
| immediate implant placement without melatonin hyaluronic acid vit C | Procedure | immediate implant placement without melatonin and hyaluronic acid and systemic administration vitamin C |
|
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| El-Gammal MY, Salem AS, Anees MM, Tawfik MA. Clinical and Radiographic Evaluation of Immediate Loaded Dental Implants With Local Application of Melatonin: A Preliminary Randomized Controlled Clinical Trial. J Oral Implantol. 2016 Apr;42(2):119-25. doi: 10.1563/aaid-joi-D-14-00277. Epub 2015 Jun 23. |