Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The aim of the present study is to evaluate dental erosion in patients with gastroesophageal reflux disease (GERD).
Patients consenting to participate to the study will undergo periodontal evaluation at the baseline. Then, professional dental hygiene will be performed. Patients will be randomly assigned to:
The aim of the present study is to evaluate dental erosion in patients with gastroesophageal reflux disease (GERD).
Patients consenting to participate to the study will undergo periodontal evaluation at the baseline. Then, professional dental hygiene will be performed. Patients will be randomly assigned to:
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Trial Group | Experimental | Domiciliary use of Biorepair Total Protection + Biorepair Shock Treatment application |
|
| Control group | Active Comparator | Domiciliary use of Biorepair Total Protection |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Domiciliary use of Biorepair Total Protection + Biorepair Shock Treatment | Other | Domiciliary use of Biorepair Total Protection twice a day for oral hygiene + Biorepair Shock Treatment application for 10 min once a day. |
| Measure | Description | Time Frame |
|---|---|---|
| Change of BEWE (Basic Erosive Wear Examination) | Scoring criteria (Barlet et al., 2008):
IntactTooth smartphone application will be used to calculate this index. | Study begin, 1, 3, 6, 9 and 12 months after the baseline |
| Change in Schiff Air Index - Dental sensitivity test | Scoring criteria: 0: the subject did not respond to air blasting;
| Study begin, 1, 3, 6, 9 and 12 months after the baseline |
| Change in Plaque Index (PI% - O' Leary Index) | Evaluation of the presence of plaque on the 4 surfaces of teeth on the total amount of dental surfaces. Formula = n ° sites with plaque / total n ° of dental surfaces x100 | Study begin, 1, 3, 6, 9 and 12 months after the baseline |
| Change in Bleeding Score (BS - Mombelli et al.) | Scoring criteria: 0: no bleeding
| Study begin, 1, 3, 6, 9 and 12 months after the baseline |
| Laryngopharyngeal pH monitoring | Data was collected wirelessly for 24 hours and then analysed. Length, severity and number of reflux episodes were calculated. The RYAN score was used to evaluate for laryngopharyngeal acid reflux and was calculated for both the upright and supine positions. A RYAN score >9.4 in the upright position or >6.8 in the supine position was considered positive. Patients with a positive RYAN score in either the upright or supine positions were considered positive for laryngopharyngeal acid reflux. |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Andrea Scribante, DDS, PhD, MS | University of Pavia | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Unit of Dental Hygiene - Section of Dentistry - Department of Clinical, Surgical, Diagnostic and Paediatrics - University of Pavia | Pavia | Lombardy | 27100 | Italy |
Data will be available upon motivated request to the Principal Investigator.
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D005764 | Gastroesophageal Reflux |
| D014077 | Tooth Erosion |
| ID | Term |
|---|---|
| D015154 | Esophageal Motility Disorders |
| D003680 | Deglutition Disorders |
| D004935 | Esophageal Diseases |
| D005767 | Gastrointestinal Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Biorepair Total Protection | Other | Domiciliary use of Biorepair Total Protection twice a day for oral hygiene + Biorepair Shock Treatment application for 10 min once a day. |
|
| Study begin, 1, 3, 6, 9 and 12 months after the baseline |
| Erosion risk level | For each sextant, the highest BEWE value will be chosen. A mean of all the sextant values will be performed to calculate erosion risk level. IntactTooth smartphone application will be used to calculate this index. | Study begin, 1, 3, 6, 9 and 12 months after the baseline |
| D004066 | Digestive System Diseases |
| D017001 | Tooth Demineralization |
| D014076 | Tooth Diseases |
| D009057 | Stomatognathic Diseases |
| D057085 | Tooth Wear |