Biomimetic Hydroxyapatite in Pediatric Patients With Asthma and/or Allergic Rhinitis

Biomimetic Hydroxyapatite vs Fluoride for the Domiciliary Oral Hygiene of Pediatric Patients With Asthma and/or Allergic Rhinitis: Randomized Clinical Trial

The aim of the study is to compare the incidence of dental caries and the level of demineralization in pediatric patients with asthma and/or allergic rhinitis.

Patients will conduct professional oral hygiene at the baseline. The following clinical indexes will be assessed: BEWE Index, Plaque Index, Bleeding Score, Schiff Air Index. Then, patients will be randomly divided into two groups:

• Trial group: domiciliary use of Biorepair Total Protection Plus + desensitizing enamel-repair shock treatment twice a day
• Control group: domiciliary use of Elmex Caries Protection twice a day

The clinical indexes will be assessed again after 1 month (T1), after 3 (T2) and 6 months (T3).

Inclusion Criteria:

• pediatric patients aged between 6-14 years
• diagnosis of allergic rhinitis and asthma
• therapy with salmeterol/fluticasone propionate
• diffused enamel demineralizations of deciduous and permanent teeth

Exclusion Criteria:

• low cooperation according to grades 3 and 4 of Frankl behavioral scale
• nonadherence to the study protocol checked by parents
• other systemic diseases.