The aim of the study is to compare white spot lesions before, during and after treatment with New Biorepair Advanced Sensitive toothpaste containing micro crystals of hydroxyapatite and Colgate toothpaste with 1450 ppm of fluoride. The timeline will consider the study begin, 15 days, 30 days and 90 days after the beginning of the study. The following indices will be recorded: BEWE Index, Schiff Air Index, VAS scale. After that, patients will fill in a satisfaction questionnaire.

The aim of the study is to compare white spot lesions before, during and after treatment with two different toothpastes for home oral care. Patients who agree to sign the informed consent will be randomly assigned to two different groups:

• Trial Group will use New Biorepair Advanced Sensitive toothpaste containing micro crystals of hydroxyapatite;
• Control Group will use Colgate toothpaste with 1450 ppm of fluoride.

At the baseline, professional oral hygiene will be performed. The following indices will be recorded at the study begin and at the following 15, 30 and 90 days: BEWE Index, Schiff Air Index, VAS scale. After that, patients will fill in a satisfaction questionnaire.

Inclusion Criteria:

• patients with white spot lesions;
• patients with dental sensibility;
• adult patients;
• patients that sign the informed consent to participate to the study.

Exclusion Criteria:

• patients with low compliance or motivation to participate to the study;
• patients not presenting white spot lesions;
• patients with absence of dental sensibility;
• patients pregnant or breastfeeding;
• underage patients;
• patients with psychiatric diseases.

Data will be available upon motivated request to Principal Investigator.