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Patients who were using anticoagulant or antiaggregant medications for any reason and underwent transurethral resection of bladder tumor (TUR-BT) or transurethral resection of the prostate (TURP) or open prostatectomy (OP) due to BPH will be compared with those who were not using anticoagulant or antiplatelet medication. The rates of postoperative clot retention, presence of hematuria, reoperation due to hematuria, blood transfusion and re-admissions due to hematuria in the first postoperative month will be compared.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| TURP patients using anticoagulant/antiaggregant medication | Patients who used anticoagulant/antiaggregant medication for any reason (eg: coronary artery disease, atrial fibrillation, cerebrovascular disease) before surgery and underwent endoscopic prostatectomy (TURP). | ||
| TURP patients not using anticoagulant/antiaggregant medication | Patients with no history of anticoagulant/antiaggregant medication and underwent endoscopic prostatectomy (TURP). | ||
| TUR-BT patients using anticoagulant/antiaggregant medication | Patients who used anticoagulant/antiaggregant medication for any reason (eg: coronary artery disease, atrial fibrillation, cerebrovascular disease) before surgery and underwent endoscopic bladder tumor resection (TUR-BT). | ||
| TUR-BT patients not using anticoagulant/antiaggregant medication | Patients with no history of anticoagulant/antiaggregant medication and underwent endoscopic bladder tumor resection (TUR-BT). | ||
| Open prostatectomy patients using anticoagulant/antiaggregant medication | Patients who used anticoagulant/antiaggregant medication for any reason (eg: coronary artery disease, atrial fibrillation, cerebrovascular disease) before surgery and underwent open prostatectomy (OP). | ||
| Open prostatectomy patients not using anticoagulant/antiaggregant medication |
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| Measure | Description | Time Frame |
|---|---|---|
| Episode of clot retention | Presence of clot retention due to hematuria after the operation which requires manuel irrigation | Immediately after the surgery up to 1 month |
| Requirement of blood transfusion | Gross hematuria requiring blood transfusion | Immediately after the surgery up to 1 month |
| Re-operation rates | Re-operation requirement for hematuria | Immediately after the surgery up to 1 month |
| Duration of hospitalization | Duration of hospitalization | Immediately after the surgery up to discharge |
| Rate of re-admission | Rate of re-admission due to hematuria | From discharge up to one month |
| Measure | Description | Time Frame |
|---|---|---|
| Postoperative hematocrit/hemoglobin levels | Change in the Postoperative hematocrit/hemoglobin levels compared to the preoperative values. | Immediately after the surgery up to discharge |
| Amount of irrigation volume |
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Inclusion Criteria:
Exclusion Criteria:
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Patients who were referred to endoscopic bladder tumor resection (TUR-BT) or open or endoscopic BPH surgery (TURP or open prostatectomy) will be included in this study. For patients using anticoagulant/antiaggregant medications, relevant specialty (eg: Cardiology, neurology, cardiovascular surgery) or anesthesiologist will decide whether the patient will quit these medications before surgery or not, when to quit and whether low molecular weight heparin will be started instead. The responsible physician of the patient will decide when to restart the anticoagulant therapy after the surgery.
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| Name | Affiliation | Role |
|---|---|---|
| Abdullah Ilktac, MD | Bezmialem Vakif University, Faculty of Medicine, Department of Urology | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bezmialem Vakif University | Istanbul | 34093 | Turkey (Türkiye) |
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Patients with no history of anticoagulant/antiaggregant medication and underwent open prostatectomy (OP). |
Amount of postoperative continuous bladder irrigation volume
| Immediately after the surgery up to discharge |
| ID | Term |
|---|---|
| D006417 | Hematuria |
| D016055 | Urinary Retention |
| D065227 | Transfusion Reaction |
| D001749 | Urinary Bladder Neoplasms |
| D011470 | Prostatic Hyperplasia |
| ID | Term |
|---|---|
| D014555 | Urination Disorders |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |
| D006470 | Hemorrhage |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D006402 | Hematologic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
| D007154 | Immune System Diseases |
| D014571 | Urologic Neoplasms |
| D014565 | Urogenital Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D001745 | Urinary Bladder Diseases |
| D011469 | Prostatic Diseases |
| D005832 | Genital Diseases, Male |
| D000091662 | Genital Diseases |
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