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The purpose of this study is to explore the predictors of ICU admission of obstetric posterior reversible encephalopathy syndrome.
The investigators retrospectively collected data (General information, clinical data, biochemical indicators, imaging features, and pregnancy outcome) from pregnant woman diagnosed with PRES to explore the predictors of ICU admission during 2012 to 2021.Then, the investigators grouped all the patients into ICU group and Non-ICU group according to ICU admission or not.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ICU group | patients admitted to ICU with PRES. |
| |
| Non-ICU group | patients not admitted to ICU with PRES. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Whether the patient needs to be admitted to the ICU | Other | According to ICU admission or not, patients were grouped into ICU group and NOT-ICU group. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Blood Pressure(BP) | blood pressure including systolic blood pressure (SBP), and diastolic blood pressure (DBP). | The BP of patients was obtained immediately at the onset of symptoms. |
| severity of the edema | The extent and severity of the edema observed in the lesion area were graded on a scale of 0-5 by evaluating FLAIR images.(0, normal; 1, limited cortical or subcortical white matter oedema; 2, white matter oedema > cortical oedema, white matter oedema extending into deep white matter; 3, white matter oedema > cortex oedema, oedema extending to the ventricular surface; 4, the involved regions substantially extend to the ventricular surface and are almost com- pletely confluent; 5, involved regions are fully confluent and con- tinuous, ventricular deformity due to the oedema). | Cranial Imaging was examined immediately at the onset of symptoms, such as s headaches, visual changes, seizures, consciousness impairment. |
| pregnancy outcomes | The rates of stillbirth and premature birth (gestation less than 37 weeks) in PRES patients. | The pregnancy outcomes will record immediately when the patients deliver. |
| biochemical parameters | The level of lactate dehydrogenase(LDH) will be measured，and LDH﹥380U/L means a worse outcome. | Biochemical indicators were collected within 1 week of the hospital stay. |
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Inclusion Criteria:
Exclusion Criteria:
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Pregnant Women diagnosed with PRES
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| Name | Affiliation | Role |
|---|---|---|
| Dunjin Chen | The Third Affiliated Hospital of Guangzhou Medical University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Obstetrics and Gynecology, Key Laboratory for Major Obstetric Diseases of Guangdong Province, The Third Affiliated Hospital of Guangzhou Medical University | Guangzhou | 510150 | China |
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| ID | Term |
|---|---|
| D054038 | Posterior Leukoencephalopathy Syndrome |
| ID | Term |
|---|---|
| D020343 | Hypertensive Encephalopathy |
| D019586 | Intracranial Hypertension |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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| D009422 | Nervous System Diseases |
| D056784 | Leukoencephalopathies |