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This study is to investigate the survival outcomes and fertility outcomes in patients with uterine low-grade endometrial stromal sarcoma (LGESS) treated in Peking Union Medical College Hospital. All primary and recurrent LGESS patients will be enrolled. The study will collect retrospectively data consisting of epidemiological characteristics, surgical, medical treatment and adjuvant therapy. Details about recurrence, mortality, pregnancy and obstetrical outcomes are also followed as primary endpoints. Fertility-sparing procedures, including uterine-sparing and ovary-sparing surgeries will be recorded specifically.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Surgical treatment with and without fertility-sparing procedures | Procedure | Patients accepted surgeries for LGESS and relevant adjuvant therapy if indicated. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Progression-free survival | Progression-free survival after surgery | One year |
| Overall survival | Overall survival after surgery | One year |
| Pregnancy rate | Pregnancy rate after surgery in patients with fertility-sparing patients | One year |
| Measure | Description | Time Frame |
|---|---|---|
| Miscarriage rate | Miscarriage rate after surgery in patients with fertility-sparing patients | One year |
| Full-term pregnancy rate | Full-term pregnancy rate after surgery in patients with fertility-sparing patients |
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Inclusion Criteria:
Exclusion Criteria:
- Not meeting all of the inclusion criteria
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Patients accepted surgical treatment with and without fertility-sparing procedures for uterine low-grade endometrial stromal sarcoma.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Lei Li, M.D. | Contact | 86-139-1198-8831 | lileigh@163.com |
| Name | Affiliation | Role |
|---|---|---|
| Lei Li, M.D. | Peking Union Medical College Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Lei Li | Recruiting | Beijing | Beijing Municipality | 100730 | China |
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| ID | Term |
|---|---|
| D036821 | Endometrial Stromal Tumors |
| D004194 | Disease |
| D012008 | Recurrence |
| ID | Term |
|---|---|
| D009372 | Neoplasms, Connective Tissue |
| D018204 | Neoplasms, Connective and Soft Tissue |
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
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| ID | Term |
|---|---|
| D013514 | Surgical Procedures, Operative |
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| One year |
| D012509 | Sarcoma |
| D016889 | Endometrial Neoplasms |
| D014594 | Uterine Neoplasms |
| D014591 | Uterine Diseases |
| D005831 | Genital Diseases, Female |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D005833 | Genital Neoplasms, Female |
| D014565 | Urogenital Neoplasms |
| D000091662 | Genital Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D020969 | Disease Attributes |