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| Name | Class |
|---|---|
| Istanbul University - Cerrahpasa | OTHER |
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In recent studies, it has been reported that intermittent theta-burst stimulation (iTBS) provides additional benefits when applied in adjunct to the rehabilitation in all stages of stroke (acute, subacute, or chronic). In our study, it was aimed to evaluate the effectiveness of iTBS applied in addition to modified constraint-induced movement therapy (mCIMT). By doing so, we intend to increase patient adherence to neurorehabilitation and decrease the cost of rehabilitation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| iTBS + mCIMT group | Experimental |
| |
| Sham iTBS+ mCIMT group | Sham Comparator |
| |
| mCIMT group | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Rehabilitation (modified constraint-induced movement therapy) | Other | Modified constraint-induced movement therapy (mCIMT): It is an intervention used to improve functionality and mobility in the more affected upper extremity post-stroke. |
| Measure | Description | Time Frame |
|---|---|---|
| Fugl-Meyer Assessment-Upper extremity | The Fugl-Meyer Assessment (FMA) is a stroke-specific, performance-based impairment index. It is designed to assess motor functioning, balance, sensation and pain. | 30 minutes |
| Wolf-Motor Function Test | It is a new time-based method to evaluate upper extremity performance while providing insight into joint-specific and total limb movements | 45 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Motor Evoked Potentials (MEPs) | MEPs are the electrical signals recorded from the descending motor pathways or from muscles following stimulation of motor pathways within the brain. | 10 minutes |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Burcu Ersöz Hüseyinsinoğlu, Assoc. Prof. | Marmara University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bakırköy Mazhar Osman Ruh ve Sinir Hastalıkları Hastanesi | Istanbul | 34394 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38329642 | Derived | Kolbasi EN, Huseyinsinoglu BE, Ozdemir Z, Bayraktaroglu Z, Soysal A. Priming constraint-induced movement therapy with intermittent theta burst stimulation to enhance upper extremity recovery in patients with stroke: protocol for a randomized controlled study. Acta Neurol Belg. 2024 Jun;124(3):887-893. doi: 10.1007/s13760-024-02472-6. Epub 2024 Feb 8. |
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| non-invasive brain stimulation (intermittent theta-burst stimulation) | Other | Intermittent theta-burst stimulation (iTBS): It is a form of repetitive transcranial magnetic stimulation and it increases the facilitation of the motor cortex. |
|
| ID | Term |
|---|---|
| D000083242 | Ischemic Stroke |
| ID | Term |
|---|---|
| D020521 | Stroke |
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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| ID | Term |
|---|---|
| D012046 | Rehabilitation |
| ID | Term |
|---|---|
| D000359 | Aftercare |
| D003266 | Continuity of Patient Care |
| D005791 | Patient Care |
| D013812 | Therapeutics |
| D006296 | Health Services |
| D005159 | Health Care Facilities Workforce and Services |
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