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| Name | Class |
|---|---|
| Nestlé Health Science Spain | INDUSTRY |
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The objective of this study is to make a comparison between 11C-acetate and 11C-Acetoacetate heart and kidney metabolism
Healthy people will have two positron emission tomography scan to perform. One, with a 11C-Acetate Tracer and the other with 11C-Acetoacetate. The results will allow to determine if both tracers are used in a similar way but the organs and see if the investigators can use the already validated analyse method for acetate to make acetoacetate analysis
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Observational heart and kidney metabolism | Other | Participants will have a PET scan with 11C-Acetate followed by a TEP Scan with 11C-Acetoacetate all in the same day. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Observational heart and kidney on siemens TEP scan | Radiation | Same as arm description |
|
| Measure | Description | Time Frame |
|---|---|---|
| Mean in left ventricule myocradial blood flow | Heart acetate metabolism measured by TEP scan | 30 minutes |
| Mean in left ventricule myocardial blood flow | Heart acetoacetate metabolism measured by TEP scan | 30 minutes |
| Mean in Kidney acetate uptake | Kidney acetate uptake measured by TEP scan | 30 minutes |
| Mean in Kidney acetoacetate uptake | Kidney acetoacetate uptake measured by TEP scan. | 30 minutes |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Research Center on Aging | Sherbrooke | Quebec | J1H 4C4 | Canada |
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| ID | Term |
|---|---|
| D007662 | Ketosis |
| ID | Term |
|---|---|
| D000138 | Acidosis |
| D000137 | Acid-Base Imbalance |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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Participants will have to perform 2 scans one after the other
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