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| Name | Class |
|---|---|
| National and Kapodistrian University of Athens | OTHER |
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Biscuits enjoy high popularity in the human diet and can be excellent snack alternatives and potential carriers of ingredients with appetite regulating properties. In the present study, the effects of a wheat biscuit enriched with plant proteins originated from legumes and seeds on gastrointestinal hormone responses of women with overweight/obesity after a hypocaloric dietary intervention will be examined.
Women with overweight/obesity will follow a 12-week dietary intervention supplemented with a cereal-based biscuit enriched with plant proteins or a common isocaloric wheat biscuit as a daily snack.
At the beginning and at the end of the dietary intervention postprandial metabolic responses, body weight reduction and subjective appetite ratings will be examined.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| wheat-based biscuit enriched with plant proteins | Experimental | Subjects follow a hypocaloric dietary intervention supplemented with certain amount of wheat-based biscuits enriched with plant proteins daily. |
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| wheat biscuit | Active Comparator | Subjects follow a hypocaloric dietary intervention supplemented with certain isocaloric amount of common wheat biscuits daily. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| wheat biscuit enriched with plant proteins | Other | Postprandial glucose and appetite-regulating hormone responses of subjects with overweight/obesity after a 12-week dietary intervention with a biscuit enriched with plant proteins |
| Measure | Description | Time Frame |
|---|---|---|
| change in postprandial glucose response | change in glucose iAUC and glucose concentration at certain time points at the end of the dietary intervention compared to the beginning. | Time points: 0,30,60,91,120,180 min postprandially at week 0 and week 12. |
| Measure | Description | Time Frame |
|---|---|---|
| change in postprandial appetite regulating hormone responses | changes in iAUCs and concentrations at certain time points at the end of the dietary intervention compared to the beginning. | Time points: 0,30,60,91,120,180 min postprandially at week 0 and week 12. |
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Inclusion Criteria:
Exclusion Criteria:
Eligibility is based on gender.
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| Name | Affiliation | Role |
|---|---|---|
| Alexander Kokkinos, Professor | National and Kapodistrian University of Athens | Study Chair |
| Amalia Yanni, PhD | Harokopio University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Laiko General Hospital, School of Medicine, National and Kapodistrian University of Athens | Athens | Attica | 11527 | Greece |
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| ID | Term |
|---|---|
| D010940 | Plant Proteins |
| ID | Term |
|---|---|
| D011506 | Proteins |
| D000602 | Amino Acids, Peptides, and Proteins |
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| common wheat biscuit | Other | Postprandial glucose and appetite-regulating hormone responses of subjects with overweight/obesity after a 12-week dietary intervention with a common wheat biscuit |
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