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Comparison of Povidone iodine and Hypochlorous acid used as a Preoperative Antiseptic in Newborn Circumcision abstract
Aim:
Circumcision is one of the most common surgical procedures in all age groups. Before the circumcision procedure, asepsis is provided with a surface disinfectant. Various methods can be used for this process. Povidone iodine, which has been used for years during the transition from traditional circumcision methods to surgical circumcision methods; tissue damage, allergic reactions and increase in pain level. For this reason, the investigators aimed to compare it with Hypochlorous acid (Crystalin), which is a less toxic and more physiological antiseptic solution.
Material and Method:
Newborns to be circumcised randomly were divided into two groups as Hypochlorosis group and Povidone iodine group. At the beginning of the circumcision procedure, a culture was taken in the form of a prepucial swab 1 minute after the cleaning of the local area and the inner surface of the prepuce. Then circumcision was performed. Culture results and complications were compared.
It is aimed to compare two solutions used for cleaning the operation area in newborn circumcision.It was conducted to compare the antibacterial activity of povidone iodine and hypochlorous.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Hypochlorosis | Active Comparator | Hypochlorosis was used as an antiseptic for the patients |
|
| Povidone iodine | Active Comparator | Povidone iodine was used as an antiseptic for the patients |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| hypochlorous acid | Drug | Randomize |
|
| Measure | Description | Time Frame |
|---|---|---|
| The effect of both drugs on wound healing will be investigated. | there is wound healing;1,no wound healing:0 | one month |
| The effect of both drugs on antibacterial effects will be investigated | there is bacterial growth:1, there is no bacterial growth:0 | one week |
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Inclusion Criteria:
Exclusion Criteria:
male
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| Name | Affiliation | Role |
|---|---|---|
| Basri Cakiroglu | Hisar Intercontinental Hospital | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hisar Intercontinental Hospital | Istanbul | 34768 | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D007239 | Infections |
| D014947 | Wounds and Injuries |
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| ID | Term |
|---|---|
| D006997 | Hypochlorous Acid |
| D011206 | Povidone-Iodine |
| ID | Term |
|---|---|
| D000148 | Acids, Noncarboxylic |
| D000143 | Acids |
| D007287 | Inorganic Chemicals |
| D017606 | Chlorine Compounds |
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Two models:Newborns to be circumcised randomly were divided into two groups as Hypochlorosis group and Povidone iodine group.
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| D017382 |
| Reactive Oxygen Species |
| D005609 | Free Radicals |
| D010087 | Oxides |
| D017601 | Oxygen Compounds |
| D007466 | Iodophors |
| D017613 | Iodine Compounds |
| D011145 | Polyvinyls |
| D014753 | Vinyl Compounds |
| D000475 | Alkenes |
| D006839 | Hydrocarbons, Acyclic |
| D006838 | Hydrocarbons |
| D009930 | Organic Chemicals |
| D011205 | Povidone |
| D011760 | Pyrrolidinones |
| D011759 | Pyrrolidines |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
| D010969 | Plastics |
| D011108 | Polymers |
| D046911 | Macromolecular Substances |
| D001697 | Biomedical and Dental Materials |
| D008420 | Manufactured Materials |
| D013676 | Technology, Industry, and Agriculture |