Wound Antiseptic Study With Hypochlorous Acid & Iodopovidone

Comparative Study of Two Antiseptics Solutions for the Prevention of Surgical Site Infection

The purpose of this study is to determine whether hypochlorous acid is an effective antiseptic agent to prevent surgical site infection.

A topical antimicrobial that decrease the bacterial bioburden of surgical wounds without impairing the wound's ability to heal is a need. A stabilized form of hypochlorous acid has been demonstrated in vitro and in animal studies to possess properties that could fulfill these criteria but it is imperative to assess its efficacy and safety in humans.

To assess hypochlorous acid efficacy and safety, it was designed a clinical controlled randomized trial to compare hypochlorous acid to iodopovidone, the gold standard, in preoperative scrub of surgical area.

Inclusion Criteria:

• All patients over 18 years old, who are going to be operated
• Classification of surgical wounds according to the National Research Council as class I or II
• Risk index classification of the American Society of Anaesthesiology (ASA) as ASA 1 or 2

Exclusion Criteria:

• Patients requiring mesh or prosthesis or orthesis