Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The aim is to determine the effect of investigational products on serum LDL cholesterol.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Active Comparator | Active Comparator | Products that contain plant stanol ester. Product with active ingredient |
|
| Placebo comparator | Placebo Comparator | Placebo product. Product without active ingredient |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Plant stanol ester | Other | Product with active ingredient vs product without active ingredient |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in low-density lipoprotein (LDL) cholesterol concentration (%) | Mean relative change in serum LDL cholesterol concentration during the intervention | 0 vs 3 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| LDL cholesterol concentration | Mean absolute change in serum LDL cholesterol concentration during the intervention between test and control group | 0 vs 3 weeks |
| total cholesterol concentration |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Helena Gylling | Helsinki University Hospital, Helsinki, Finland | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Nightingale Health plc | Helsinki | 00330 | Finland |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D006937 | Hypercholesterolemia |
| ID | Term |
|---|---|
| D006949 | Hyperlipidemias |
| D050171 | Dyslipidemias |
| D052439 | Lipid Metabolism Disorders |
| D008659 | Metabolic Diseases |
Not provided
Not provided
| ID | Term |
|---|---|
| C407042 | plant stanol ester |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Placebo | Other | Placebo |
|
Changes in serum total cholesterol concentration during the intervention
| 0 vs 3 weeks |
| High density lipoprotein (HDL) cholesterol concentration | Changes in serum HDL cholesterol concentration during the intervention | 0 vs 3 weeks |
| non-HDL cholesterol concentration | Changes in serum non-HDL cholesterol concentration during the intervention | 0 vs 3 weeks |
| Total triglyceride concentration | Changes in serum triglycerides concentrations | 0 vs 3 weeks |
| Nuclear magnetic resonance (NMR) blood biomarkers | Changes in specific NMR blood biomarkers | 0 vs 3 weeks |
| D009750 |
| Nutritional and Metabolic Diseases |