Lipid Lowering Effect of a Cereal Based Snack Bar With Added Plant Stanol Ester

Effect of a Cereal Based Snack Bar With Added Plant Stanol Ester on Serum Total and Lipoprotein Lipids

The purpose of the study is to investigate the cholesterol lowering efficacy of a cereal based snack bar with added plant stanol ester when used between meals as part of a habitual diet by subjects with mild to moderate hypercholesterolemia.

Inclusion Criteria:

• Serum total cholesterol 5.2-8.5 mmol/l
• Serum triglycerides < 3 mmol/l
• Signed written informed consent

Exclusion Criteria:

• Abnormal liver, kidney and thyroid function
• Use of lipid lowering medication
• Consumption of other plant sterol or plant stanol containing food products or supplements, or other foods or supplements for cholesterol lowering 1 month prior to visit 2
• History of unstable coronary artery disease (myocardial infarction, coronary artery bypass graft (CABG), percutaneous transluminal coronary angioplasty (PTCA) within the previous 6 months
• Diagnosed type 1 or type 2 diabetes requiring medical treatment
• History of recent temporal ischemic attack or malignant diseases (< 5 yrs)
• Celiac disease, or allergy or intolerance to the ingredients of the test products
• Medically prescribed diet/medication for slimming or a special diet like very low calorie diet or obesity drug, or vegan and gluten-free diet
• Subjects with alcohol abuse (> 4 portion per day)
• Pregnancy or planned pregnancy or lactating