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| Name | Class |
|---|---|
| Mahidol University | OTHER |
Efficacy of plant stanols as esters on LDL-cholesterol reduction is well documented. LDL-cholesterol lowering efficacy of the ingredient in a biscuit (providing 2 g plant stanols as esters per day) is less well known.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Placebo biscuit | Placebo Comparator | Biscuit without plant stanol ester |
|
| Plant stanol ester biscuit | Experimental | Biscuit with plant stanol esters |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Plant stanol ester | Dietary Supplement |
| ||
| Placebo |
| Measure | Description | Time Frame |
|---|---|---|
| Change (proportional) in LDL-c from baseline after 4-weeks' plant stanol ester biscuit consumption compared to controls | 4 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Change (proportional) in LDL-c from baseline after 4-weeks' plant stanol ester biscuit consumption in subjects consuming the biscuit with or without a meal | 4 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Wantanee Kriengsinyos, PhD | Mahidol University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Mahidon University, Nutrition Institute, Center of Innovation and Reference on Food for Nutrition (CIRFON) | Phutthamonthon | Changwat Nakhon Pathom | 73170 | Thailand |
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| ID | Term |
|---|---|
| D050171 | Dyslipidemias |
| D006937 | Hypercholesterolemia |
| D006949 | Hyperlipidemias |
| ID | Term |
|---|---|
| D052439 | Lipid Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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| ID | Term |
|---|---|
| C407042 | plant stanol ester |
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