This randomized, placebo-controlled, double-blind, and cross-over study was designed to check whether the roselle-based drink (2 bottles every day) can alter blood pressure and skin condition in elderly healthy subjects.

The subjects were assigned into two groups (control group and test group), each group subject was requested to drink 2 bottles every day (100 mL/bottle, one in the morning and another in the evening), the rate of drinking is 75.42%. There are 39 subjects (25 females and 14 males) completely involved in the thirteen-month trial (cross-over). Blood samples were collected at the initial, 3rd, 6th, 7th, 10th, 13th months of the trial. Skin examinations were performed at the initial, 6th, 7th, 13th months.

Inclusion Criteria:

• Healthy adults
• Subjects should not be under any medication
• Subject must be able to drink

Exclusion Criteria:

• Subjects with chronic renal, liver or cardiac disorders, Diabetes, hyperlipidemia.
• Also pregnant women, chain smokers, high alcohol consumers should not be included.