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To assess a resveratrol formula on improvement of skin conditions and inflammatory cytokines in blood
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Resveratrol drink | Experimental |
| |
| Placebo drink | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Resveratrol drink | Dietary Supplement | Subjects will consume a bottle of resveratrol drink for two months. |
|
| Measure | Description | Time Frame |
|---|---|---|
| The change of skin moisture | Corneometer® CM825 was utilized to measure skin moisture. Units: arbitrary Corneometer® units 0-120 | 0, 4, and 8 weeks |
| The change of skin elasticity | Cutometer® dual MPA 580 was utilized to measure skin elasticity (parameter R2). Units: μm penetration depth into the probe opening, expressed as curves | 0, 4, and 8 weeks |
| The change of skin wrinkles | VISIA Complexion Analysis System was utilized to measure wrinkles. Units: arbitrary units | 0, 4, and 8 weeks |
| The change of skin collagen density | DermaLab® USB - 20 MHz High Freq. Ultrasound probe was utilized to scan and analyze skin collagen density. Units: Intensity score | 0, 4, and 8 weeks |
| The change of skin texture | VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units | 0, 4, and 8 weeks |
| The change of skin pores | VISIA Complexion Analysis System was utilized to measure skin pores. Units: arbitrary units | 0, 4, and 8 weeks |
| The change of total antioxidant capacity of blood | Total Antioxidant Capacity Assay Kit | 0 and 8 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Chia Nan University of Pharmacy & Science | Tainan | 71710 | Taiwan |
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| ID | Term |
|---|---|
| D012871 | Skin Diseases |
| ID | Term |
|---|---|
| D017437 | Skin and Connective Tissue Diseases |
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| Placebo drink | Dietary Supplement | Subjects will consume a bottle of placebo drink for two months. |
|
| The change of TNF-alpha of blood |
ELISA Kit |
| 0 and 8 weeks |
| The change of IL-6 of blood | ELISA Kit | 0 and 8 weeks |
| The change of IL-17 of blood | ELISA Kit | 0 and 8 weeks |
| The change of IL-1β of blood | ELISA Kit | 0 and 8 weeks |