Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
To assess Chenopodium Formosanum and Fagopyrum Esculentum Extract on skin anti-aging
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Placebo drink | Placebo Comparator |
| |
| Chenopodium Formosanum and Fagopyrum Esculentum Extract drink | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Placebo drink | Dietary Supplement | consume 2 bottle (30 mL) per day for 56 days |
| |
| Measure | Description | Time Frame |
|---|---|---|
| The change of skin moisture | Corneometer® CM825 is utilized to measure skin moisture. Units: arbitrary Corneometer® units 0-120 | Change from Baseline skin moisture at 8 weeks |
| The change of skin elasticity | Cutometer® dual MPA 580 is utilized to measure skin elasticity (parameter R2). Units: μm penetration depth into the probe opening, expressed as curves | Change from Baseline skin elasticity at 8 weeks |
| The change of skin wrinkles | 3D Full-Face Skin Analyzer IRV is utilized to measure wrinkles. Units: arbitrary units | Change from Baseline skin wrinkles at 8 weeks |
| The change of skin collagen density | DermaLab® combo - 20 MHz High Freq. Ultrasound probe is utilized to scan and analyze skin collagen density. Units: Intensity score | Change from Baseline skin collagen density at 8 weeks |
| The change of skin tone | 3D Full-Face Skin Analyzer IRV was utilized to measure skin tone. Units: arbitrary units | Change from Baseline skin tone at 8 weeks |
| The change of skin brightness | 3D Full-Face Skin Analyzer IRV is utilized to measure skin brightness. Units: arbitrary units | Change from Baseline skin brightness at 8 weeks |
| The change of skin melanin index | Mexameter® MX 18 is utilized to measure skin melanin index. Units: arbitrary Mexameter® units (0-999) |
| Measure | Description | Time Frame |
|---|---|---|
| The change of transepidermal water loss (TEWL) | Tewameter® TM 300 is utilized to measure transepidermal water loss. Units: g/hm² | Change from Baseline TEWL at 8 weeks |
| The change of skin texture |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Hsiu-Mei Chiang, Prof. | China Medical University, China | Principal Investigator |
| Po-Yuan Wu, Dr. | China Medical University Hospital | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| China Medical University | Taichung | 404 | Taiwan |
Not provided
| ID | Term |
|---|---|
| D012871 | Skin Diseases |
| ID | Term |
|---|---|
| D017437 | Skin and Connective Tissue Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Chenopodium Formosanum and Fagopyrum Esculentum Extract drink |
| Dietary Supplement |
consume 2 bottle (30 mL) per day for 56 days |
|
| Change from Baseline skin melanin index at 8 weeks |
| The change of skin L*a*b* value | Color Spectrophotometer SCM-104/108 is utilized to measure skin L*a*b* value. Units: arbitrary units | Change from Baseline skin L*a*b* value at 8 weeks |
3D Full-Face Skin Analyzer IRV is utilized to measure skin texture. Units: arbitrary units
| Change from Baseline skin texture at 8 weeks |
| The change of skin pores | 3D Full-Face Skin Analyzer IRV is utilized to measure skin pores. Units: arbitrary units | Change from Baseline skin pores at 8 weeks |
| The change of skin spots | 3D Full-Face Skin Analyzer IRV is utilized to measure skin spots. Units: arbitrary units | Change from Baseline skin spots at 8 weeks |
| The change of skin erythema level | Mexameter® MX 18 is utilized to measure skin erythema level. Units: arbitrary Mexameter® units (0-999) | Change from Baseline skin erythema level at 8 weeks |
| Self-assessment questionnaire | Questionnaire is utilized to assess skin condition of the subjects. Units: score | 8 weeks |