Thyroid Gland Dysfunction and Vitamin D Polymorphism in Keratoconus

Thyroid Gland Dysfunction and Vitamin D Receptor Polymorphism in Keratoconus

This prospective study the thyroid gland dysfunction and vitamin D receptor polymorphism in keratoconus patients

This is a prospective observational study in which blood samples are collected from keratoconus patients looking for thyroid dysfunction and vitamin D levels in the serum and assessing the Vitamin D receptor polymorphism in comparison to healthy control.

Inclusion Criteria:

• keratoconus patients without previously diagnosed thyroid disorder in comparison to healthy control without known systemic disease and with normal cornea who were selected from candidates of refractive surgery with normal topography

Exclusion Criteria:

• patients who could not provide informed consent or the necessary samples for any reason, patients with associated other ophthalmic pathologies or systemic disorders were excluded from the study