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Systemic lupus erythematosus is a chronic and multisystemic autoimmune disorder which predominantly affecting women. The most common cause of death in lupus patients affected by disease for more than 5 years is cardiovascular disease due to presence of some factors as oxidative stress, pro-inflammatory cytokines , dyslipidemia, diabetes, and hypertension.
laser acupuncture (active or sham) for one month (3 days/week ) on acupoint number 14 of GV meridian, acupoint number 4 and 11 of large intestine, acupoint number 34 of gall bladder meridian, acupoint number 3 of liver meridian, acupoint number 4, 12, and 9 of conception vessel meridian, acupoint number 40, 36, and 25 of stomach meridian, acupoint number 6 of spleen meridian, and acupoint number 5 of triple energizer meridian (laser will be applied for 1 min on every acupiont) in lupus females
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| group 1 | Active Comparator | thirty lupus women received laser acupuncture (active) for one month (3 days week) on acupoint number 14 of GV meridian, acupoint number 4 and 11 of large intestine, acupoint number 34 of gall bladder meridian, acupoint number 3 of liver meridian, acupoint number 4, 12, and 9 of conception vessel meridian, acupoint number 40, 36, and 25 of stomach meridian, acupoint number 6 of spleen meridian, and acupoint number 5 of triple energizer meridian (laser was applied for 1 min on every acupiont). |
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| group 2 | Sham Comparator | thirty lupus women received laser acupuncture (sham) for one month (3 days) on acupoint number 14 of GV meridian, acupoint number 4 and 11 of large intestine, acupoint number 34 of gall bladder meridian, acupoint number 3 of liver meridian, acupoint number 4, 12, and 9 of conception vessel meridian, acupoint number 40, 36, and 25 of stomach meridian, acupoint number 6 of spleen meridian, and acupoint number 5 of triple energizer meridian (laser was be applied for 1 min on every acupiont). |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| laser application on acupoints | Device | laser acupuncture |
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| Measure | Description | Time Frame |
|---|---|---|
| Malondialdehyde | anti-oxidative stress factor | It was measured after 4 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| systole | blood pressure | It was measured after 4 weeks |
| diastole | blood pressure | It was measured after 4 weeks |
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Inclusion Criteria:
Exclusion Criteria:
self-representation of gender identity.
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| Name | Affiliation | Role |
|---|---|---|
| Ali Ismail, lecturer | Cairo University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Physical Therapy Cairo University | Giza | Dokki | Egypt |
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| ID | Term |
|---|---|
| D008180 | Lupus Erythematosus, Systemic |
| ID | Term |
|---|---|
| D003240 | Connective Tissue Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
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| blood glucose | fasting | It was be measured after 4 weeks |
| erythrocyte sedimentation rate (1 hour) | inflammatory marker | It was measured after 4 weeks |
| erythrocyte sedimentation rate (2 hour) | inflammatory marker | It was measured after 4 weeks |
| c reactive protein | inflammatory marker | It was measured after 4 weeks |
| adenosine triphosphate | energy production marker | It was measured after 4 weeks |
| Nitrate | oxidative stress factor | It was measured after 4 weeks |
| Glutathione | antioxidant marker | It was measured after 4 weeks |