This study will evaluate the effect of low level laser blood radiation applied to all participants for prevention of coronary artery disease in patients with high risk (hypertension,high blood viscosity, hypercholesterolemia as well as related immune issues)

The areas of low - intensity laser use have expanded in several conditions by different mechanisms and ways. Hypertension as one of coronary artery disease risk factors and early indicator of future cardiovascular events with high blood viscosity and elevated blood cholesterol levels with immune-pathological basis became necessary issue to be handled. Low Level Laser irradiation effects on blood is very essential way in revealing the mechanisms of the action of laser radiation on biological tissues by means of changes in metabolism, leading to molecular, cellular and systemic changes.

Inclusion Criteria:

• stage I hypertensive patients
• patients from 30 to 34.9 kg/m2 body mass index
• medically stable patients
• all participants have sufficient cognition enough to understand the requirements of the study

Exclusion Criteria:

• history of malignant disease
• smoking
• history of progressive fatal disease
• history of drug or alcohol abuse
• blood donation within at least 30 days
• pregnant, trying to be pregnant or breast feeding
• cognitive impairment that will make it difficult to partake in the study

De-identified participated data for underlie results reported in this trial

data will be available after 6 months of study completion and ending 36 months

proposals should directed to Dr.EbtesamNagy@cu.edu.eg. To gain access, data requestors will need to sign a data access agreement