Gustatory Modulators Among a Sample of Depressed Egyptian Adults Under Anti-depressants Therapy

Gustatory Modulators Among a Sample of Depressed Egyptian Adults Under Anti-depressants Therapy. A Retrospective Cohort Study

Identify possible modulators for developing gustatory dysfunction among a sample of depressed Egyptian adults (age from 20 to 50 years old) under anti-depressants therapy ( for at least 3 months) using a questionnaire ( appendix) with a binary measuring unit (yes/no).

PECO

• P Population: depressed Egyptian adults under anti-depressants therapy
• E1 Exposure 1: commonly prescribed tricyclic antidepressants (Imipramine, Amitriptyline, Clomipramine HCL)
• E2 Exposure 2: commonly prescribed Selective Serotonin Re-uptake inhibitors antidepressants ( Fluoxetine, Fluvoxamine, Sertraline, Citalopram, Paroxetine)
• C control (non exposure) : non-pharmacological treatment ( psychotherapy)
• O Outcome: Identify possible gustatory dysfunction modulators among these patients using a questionnaire ( appendix) with a binary measuring unit (yes/no).

Inclusion Criteria:

• • Depressed Egyptian adults under antidepressants therapy for at least 3 months/non-pharmacological treatment( psychotherapy)

  • Age from 20 to 50 years old

Exclusion Criteria:

• Antipsychotics

  • Hypnotics
  • Anticonvulsants
  • Ages other than the mentioned • Olfactory dysfunction
  • Chemosensory dysfunction