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Caffeine consumption has been linked to dysfunction of the autonomic nervous system. In this study the investigators analyze the effects of caffeine containing drinks (including energy drinks and coffee) on ECG based parameters of the autonomic nervous system.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Coffee | Experimental | Oral consumption of 3 cups of coffee containing 240 mg caffeine |
|
| Energy drink | Experimental | Oral consumption of 750 mL of a commercial energy drink containing 240 mg caffeine |
|
| Placebo | Placebo Comparator | Oral consumption of 750 mL water |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| caffeine | Dietary Supplement | oral consumption |
|
| Measure | Description | Time Frame |
|---|---|---|
| Heart rate (HR) | ECG-based analysis of heart rate (beats per minute) | 2 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Periodic repolarization dynamics (PRD) | ECG-based analysis of repolarization instability (deg²) | 2 hours |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospital Munich (LMU Klinikum) | Munich | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35266046 | Derived | Schuttler D, Rudi WS, Bauer A, Hamm W, Brunner S. Impact of energy drink versus coffee consumption on periodic repolarization dynamics: an interventional study. Eur J Nutr. 2022 Aug;61(5):2847-2851. doi: 10.1007/s00394-022-02853-8. Epub 2022 Mar 10. |
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| ID | Term |
|---|---|
| D002110 | Caffeine |
| ID | Term |
|---|---|
| D014970 | Xanthines |
| D000470 | Alkaloids |
| D006571 | Heterocyclic Compounds |
| D011688 | Purinones |
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| D011687 |
| Purines |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |