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| Name | Class |
|---|---|
| Giuseppe Calcagno | UNKNOWN |
| Giovanni Fiorilli | UNKNOWN |
| Andrea Buonsenso | UNKNOWN |
| Marco Centorbi |
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The aim is to establish adequate and suitable protocols for PD patients and to determine the WB-EMS effects on muscle strength, balance, walking, cognitive functions,neurotrophic factors and alpha-synuclein. Thirty-six PD patients, aged from 50 to 80 years, will be recruited and randomly assigned to two experimental groups (EGs and EGc) and one control group (CG), in order to perform dynamic movements with WB-EMS. EGs will undergo to 12-20 minutes of progressive supervised WB-EMS (4 sec. 85 HZ and 4 sec. rests) combined to light dynamic movements, two-time per week for 12/24 weeks. EGe will undergo to 12-20 minutes of progressive supervised WB-EMS 7 Hz) combined with cardiovascular training with rowing machine. CG will not perform any type of physical activity. Pre and post intervention assessment will be carried out on the following areas: physical assessment, neurocognitive, neurotrophic factors and alpha-synuclein assesments. A 3 months follow-up will be performed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| "Strength training + WB-EMS" | Experimental | Strength training combined with WB-EMS : 2 times/week for 20 minutes |
|
| Cardiovascular training + WB-EMS | Experimental | Cardiovascular training, using rowing machine, combined with WB-EMS : 2 times/week for 20 minutes |
|
| Control group | Active Comparator | No physical activity |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Strenght training combined with WB-EMS | Other | Bodyweight exercise training combined with WB-EMS (2 times/week) with a 85Hz electrical impulse |
|
| Measure | Description | Time Frame |
|---|---|---|
| REPETITIONS NUMBER CHANGE | 30S ARM CURL TEST | 14 Weeks |
| REPETITIONS NUMBER CHANGE | 30S SIT TO STAND TEST; | 14 Weeks |
| TIME(S) CHANGE | SODA POP TEST ; | 14 Weeks |
| TIME(S) CHANGE | 8 FEET UP AND GO TEST ; | 14 Weeks |
| DISTANCE (M) CHANGE | 6 MINUTE WALKING TEST | 14 Weeks |
| UPPER LIMB STRENGHT CHANGE | HAND GRIP TEST | 14 Weeks |
| LOWER BODY FLEXIBILITY | CHAIR SIT AND REACH TEST | 14 Weeks |
| BALANCE AND STABILITY TEST CHANGE | TINETTI BALANCE AND GAIT EVALUATION TEST | 14 Weeks |
| NUMBER OF ERRORS CHANGE | STROOP TEST; | 14 Weeks |
| NUMBER OF ERRORS CHANGE |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Alessandra di Cagno | Università degli studi di Roma Foro Italico | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Università degli Studi del Molise | Campobasso | 86100 | Italy |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38588457 | Derived | Ernst M, Folkerts AK, Gollan R, Lieker E, Caro-Valenzuela J, Adams A, Cryns N, Monsef I, Dresen A, Roheger M, Eggers C, Skoetz N, Kalbe E. Physical exercise for people with Parkinson's disease: a systematic review and network meta-analysis. Cochrane Database Syst Rev. 2024 Apr 8;4(4):CD013856. doi: 10.1002/14651858.CD013856.pub3. | |
| 36845654 |
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| ID | Term |
|---|---|
| D010300 | Parkinson Disease |
| ID | Term |
|---|---|
| D020734 | Parkinsonian Disorders |
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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| ID | Term |
|---|---|
| D035061 | Control Groups |
| ID | Term |
|---|---|
| D015340 | Epidemiologic Research Design |
| D004812 | Epidemiologic Methods |
| D008919 | Investigative Techniques |
| D012107 | Research Design |
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| UNKNOWN |
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| Cardiovascular training with WB-EMS | Other | Cardiovascular training , using the rowing machine, combined with WB-EMS (2 times/week) with a 7Hz electrical impulse |
|
| Control group | Other | No physical activity |
|
REY AUDITORY VERBAL LEARNING TEST |
| 14 Weeks |
| TIME(S) CHANGE | STROOP TEST | 14 Weeks |
| TIME(S) CHANGE | TRAIL MAKING TEST CHANGE | 14 Weeks |
| NEUROTROPHIC FACTORS CHANGE | BLOOD DRAW | 14 Weeks |
| ALPHA-SYNUCLEIN CHANGE | BLOOD DRAW | 14 Weeks |
| di Cagno A, Buonsenso A, Centorbi M, Manni L, Di Costanzo A, Casazza G, Parisi A, Guerra G, Calcagno G, Iuliano E, Soligo M, Fiorilli G; WB-EMS Parkinson's Group. Whole body-electromyostimulation effects on serum biomarkers, physical performances and fatigue in Parkinson's patients: A randomized controlled trial. Front Aging Neurosci. 2023 Feb 9;15:1086487. doi: 10.3389/fnagi.2023.1086487. eCollection 2023. |
| 36602886 | Derived | Ernst M, Folkerts AK, Gollan R, Lieker E, Caro-Valenzuela J, Adams A, Cryns N, Monsef I, Dresen A, Roheger M, Eggers C, Skoetz N, Kalbe E. Physical exercise for people with Parkinson's disease: a systematic review and network meta-analysis. Cochrane Database Syst Rev. 2023 Jan 5;1(1):CD013856. doi: 10.1002/14651858.CD013856.pub2. |
| D009422 | Nervous System Diseases |
| D009069 | Movement Disorders |
| D000080874 | Synucleinopathies |
| D019636 | Neurodegenerative Diseases |
| D008722 | Methods |