Knee pain is one of the most usual pain that commonly affects people especially in the late age. It can be caused by osteoarthritis, poor posture or sitting position, bad bending or improper lifting. It is usually not caused by a serious illness. It is the most common cause of disability. To compare the long term effects of Mulligan Mobilization with Movement versus Macquarie Injury Management Group on pain and function of knee osteoarthritis.

It was a randomized clinical trial conducted in Revival Physiotherapy Center, Lahore. A convenient sample of 26 diagnosed patients with osteoarthritis was included in the study. Subjects were randomly distributed in to two groups with use of flip coin method Group of randomization. Group 1 patients got MIMG with routine physical therapy and Group 2 got MWM with routine physical therapy. Visual analogue Scale (VAS),Non modified WOMAC were used to assess all patients before and after 4 weeks of intervention. Statistical analysis was computed by SPSS 20.0.

Inclusion Criteria:

• ACR criteria for knee will be over age 50
• less than 30 minutes of morning stiffness,
• Crepitus on active motion,
• Tenderness
• Enlargement
• No palpable warmth of synovium.
• Osteoarthritis grade 1 and 2 by Kelly-green and Lawrence method.

Exclusion Criteria:

• Any surgical procedure done in past 6 months and metal implants in lower extremity.
• Any infection and neoplastic disorder.
• Post traumatic knee stiffness.
• Secondary knee O A peripheral vascular disease