Effect of Amnion Membrane With and Without Taurine on GCF TNF α Level.

Efficacy of Subgingivally Placed Amnion Membrane With and Without Taurine as an Adjunct to Scaling and Root Planing in the Treatment of Chronic Periodontitis

45 sites in 15 patients with periodontal pockets ≥ 5mm were selected. These selected sites were divided into 3 groups as Group A, B and C.

Group A (Control): 15 sites received only SRP, Group B: 15 sites received SRP with subgingival placement of amnion membrane, Group C: 15 sites received SRP with subgingival placement of Amnion membrane hydrated with Taurine.

Inclusion Criteria:

•Systemically healthy patients with sites showing probing depth (PD) ≥ 5mm, clinical attachment level (CAL) ≥ 4 mm, and vertical bone loss ≥ 3 mm on intraoral periapical radiographs with no history of periodontal therapy or use of antibiotics in the preceding 6 months

Exclusion Criteria:

• Any systemic disease that could influence the outcome of periodontal therapy.
• Smokers, alcoholics & patients with other adverse habits.
• Pregnant or nursing women.
• Any known allergy or hypersensitivity to any product used in the study.
• Patients on long term systemic therapy (antibiotics, anti-inflammatory and any other).