Impact of Underlying Renal Disease and Immunosuppressive Regimen on Ovarian Reserve in Renal Patients

Impact of the Immunosuppressive Treatment, X-ray Exposition and Renal Pathology on Ovarian Reserve in Young Women

Aging, renal pathology (eg SLE, ADPKD), X-ray exposition and pharmacological treatments, especially previous strong immunosuppression, may negatively influence the ovarian reserve in childbearing age women. Anti-Müllerian hormone (AMH) is regarded as biomarker for ovarian reserve.

Every female with renal disease regularly menstruating that met exclusion criteria could have participated. The aim was to assess ovarian reserve in female patients with normal menstrual cycle and kidney disease, including kidney transplant recipients.

Inclusion Criteria:

• Conscious written approval
• Autoimmunological disorder with kidneys affection/ kidney transplant recipient- Regular menstrual cycles
• Age above 18 years old

Exclusion Criteria:

• Irregular menstrual cycles
• Menopause
• PCOS
• Chemiotherapy or radiotherapy in the past
• Surgical interventions within ovaries
• Hypogonadotropic hypogonadism
• Folliculoma
• Age under 18 years old