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Crohn's disease reduces fertility by inducing inflammation both directly and in the fallopian tubes and ovaries and indirectly through surgical interventions and tubal adhesions associated with disease treatment. Anti-mullerian hormone (AMH) is a reliable indicator of ovarian reserve in women. The aim of this study was to compare serum AMH levels in women with Crohn's disease and healthy controls. In this study, the investigators aimed to investigate AMH and ovarian capacity in the study group with crohn's disease and in the control group without disease.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| study group | women in reproductive age with crohn's disease |
| |
| control group | women in reproductive age without crohn's disease, |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| AMH levels in young women with crohn's disease will be considered. | Other | Ovarian Reserve in Young Women of Reproductive Age with Crohn's Disease;Blood will be taken from both the study and control groups and the AMH level will be evaluated. |
| Measure | Description | Time Frame |
|---|---|---|
| AMH levels | AMH levels of subjects taken into groups will be evaluated in lg/L | 1 MONTH |
| Measure | Description | Time Frame |
|---|---|---|
| ultrasound findings | On the 3rd day of the menstrual cycle, the patients will be given ultrasound and the ovarian volume will be examined. the ovarian volume will be calculated by taking the size of the ovary in three sections. | 1 MONTH |
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Inclusion Criteria:
Exclusion Criteria:
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The study group consisted of young women in the reproductive age with crohn's disease.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kanuni Sultan Süleyman Training and Research Hospital | Istanbul | 33404 | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D003424 | Crohn Disease |
| D010049 | Ovarian Diseases |
| ID | Term |
|---|---|
| D015212 | Inflammatory Bowel Diseases |
| D005759 | Gastroenteritis |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
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| D007410 | Intestinal Diseases |
| D000291 | Adnexal Diseases |
| D005831 | Genital Diseases, Female |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D000091662 | Genital Diseases |
| D006058 | Gonadal Disorders |
| D004700 | Endocrine System Diseases |