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ECCO consensus, the fertility would decline in activity inflammatory bowel disease(IBD), because of anus lesions and pelvic abscess, or who underwent surgery, especially in patients with ileal pouch anal anastomosis (IPAA) storage.The study on fertility in inflammatory bowel disease were almost epidemiological investigation, the lack of objective evaluation of fertility, and controversial.This study will explore the fertility, ovarian reserve function and the pregnancy outcomes in patients with IBD.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| IBD patients | Experimental | IBD patients, 17-40 years old, female |
|
| healthy control | Other | 17-40 years old , female, without any gynecological disease |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Anti Mueller hormone | Other | used to assess ovarian reserve parameters |
|
| Measure | Description | Time Frame |
|---|---|---|
| The AMH of IBD patients is lower than that of healthy women | AMH is used to assess ovarian reserve function | 1 month |
| The E2 of IBD patients is lower than that of healthy women | E2 is used to assess ovarian reserve function | 1 month |
| The FSH of IBD patients is lower than that of healthy women | FSH is used to assess ovarian reserve function | 1 month |
| The AFC of IBD patients is lower than that of healthy women | AFC is used to assess ovarian reserve function | 1 month |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| xiang peng, MM | Contact | 18302076916 | stefaniepx@163.com |
| Name | Affiliation | Role |
|---|---|---|
| Min Zhi, PHD | The Sixth Affiliated Hospital of Zhongshan University | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The Sixth Affiliated Hospital of Zhongshan University | Recruiting | Guangzhou | Guangdong | 510000 | China |
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| Estrogen | Other | used to assess ovarian reserve parameters |
|
| Follicle-Stimulating Hormone | Other | used to assess ovarian reserve parameters |
|
| Antral alveolar cell count | Other | used to assess ovarian reserve parameters |
|
| ID | Term |
|---|---|
| D004967 | Estrogens |
| D005640 | Follicle Stimulating Hormone |
| ID | Term |
|---|---|
| D006728 | Hormones |
| D006730 | Hormones, Hormone Substitutes, and Hormone Antagonists |
| D045505 | Physiological Effects of Drugs |
| D020228 | Pharmacologic Actions |
| D020164 | Chemical Actions and Uses |
| D006065 | Gonadotropins, Pituitary |
| D006062 | Gonadotropins |
| D036361 | Peptide Hormones |
| D010908 | Pituitary Hormones, Anterior |
| D010907 | Pituitary Hormones |
| D010455 | Peptides |
| D000602 | Amino Acids, Peptides, and Proteins |
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