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| Name | Class |
|---|---|
| Turkish Respiratory Society | UNKNOWN |
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The investigators hypothese that lung involvement due to COVID-19 may cause structural changes in the lung in the long term. In this study the effects of structural changes in the lung on pulmonary function tests, exercise capacity and quality of life will be examined.
Coronavirus disease-19 (COVID-19) has a clinical spectrum ranging from asymptomatic cases to severe cases requiring intensive care hospitalization due to respiratory failure. The disease mostly infects the lower respiratory tract. Typical computed tomography findings of lung involvement are bilateral, peripherally located ground glass density and consolidations. There is a close relationship between tomography findings and clinical severity. It is not known whether there will be complete recovery in the lungs.
Investigators will evaluate pulmonary structures with chest computed tomography, respiratory capacity with pulmonary function tests (PFTs), exercise capacity with six minutes walk test and quality of life with short form-36 (SF-36) im patients who survivors of COVID-19 at least 6 months after hospital discharge.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients in ICU | ICU patients with COVID-19 |
| |
| Patients in Hospital Ward | Patients with COVID-19 in hospital wards |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Chest Computed Tomography | Diagnostic Test | Evaluation of Lung Structure |
|
| Measure | Description | Time Frame |
|---|---|---|
| Structural Change in Lung | Chest Computed Tomography | up to 6 months after discharge |
| Measure | Description | Time Frame |
|---|---|---|
| Carbon monoxide diffusion capacity (DLCO) | Carbon monoxide diffusion capacity of the lung | up to 6 months after discharge |
| Exercise Capacity | Six Minutes Walking Test |
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Inclusion Criteria:
Exclusion Criteria:
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Survivors of COVID-19 aged over 18 years old who had been admitted in University of Health Sciences, Dr. Suat Seren Chest Disease and Surgery Training and Research Hospital for COVID-19 patients in İzmir, Turkey.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| 1University of Health Sciences Turkey, Dr Suat Seren Chest Diseases and Chest Surgery Training and Research Hospital, Intensive Care Unit | Izmir | 35110 | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D000086382 | COVID-19 |
| ID | Term |
|---|---|
| D011024 | Pneumonia, Viral |
| D011014 | Pneumonia |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
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| ID | Term |
|---|---|
| D012129 | Respiratory Function Tests |
| D011788 | Quality of Life |
| ID | Term |
|---|---|
| D003948 | Diagnostic Techniques, Respiratory System |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D006304 | Health Status |
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| Pulmonary Function Tests | Diagnostic Test | Respiratory Capacity |
|
| Six Minutes Walk Test | Other | Exercise Capacity |
|
| Quality of Life | Other | Physical disability assessment tool |
|
|
| up to 6 months after discharge |
| Short Form Health Survey Score (SF-16) | A 36-item patient-reported questionnaire that covers eight health domains: physical functioning (10 items), bodily pain (2 items), role limitations due to physical health problems (4 items), role limitations due to personal or emotional problems (4 items), emotional well-being (5 items), social functioning (2 items), energy/fatigue (4 items), and general health perceptions (5 items). Scores for each domain range from 0 to 100, with a higher score defining a more favorable health state | up to 6 months after discharge |
| D014777 |
| Virus Diseases |
| D018352 | Coronavirus Infections |
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D003710 | Demography |
| D015991 | Epidemiologic Measurements |
| D011634 | Public Health |
| D004778 | Environment and Public Health |