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First, preoperative biometry of the eye at the IOL Master® will be performed. Then, corneal topography will be measured at the Oculus pentacam®. Afterwards, one of two eye drops are instilled in the eye, and biometry and corneal topography will be repeated after 5 minutes.
For all patients, the Barrett Universal II formula will be used for calculation of IOL power. Predicted refraction outcome will be referred to as SEQ. The chief surgeon will perform the uneventful standard cataract operation with in-the-bag implantation of a HOYA IOL (Model 251) through a 2.4-mm corneal incision.
A Subjective Refraction using plus principle will be performed one month after the operation, and ETDRS visual acuity charts will be used to measure best-corrected visual acuity. Refraction will be described as SR (postoperative SEQ) and will be calculated as:
SR = sphere + (0.5*cylinder)
First, preoperative biometry of the eye at the IOL Master® will be performed. Then, corneal topography will be measured at the Oculus pentacam®. Patients will be classified as dry eye or normal eye based on BUT. The tear film breakup (BUT) time of less than 5 seconds will be diagnosed as dry eyes.Afterwards, one of two eye drops are instilled in the eye, and biometry and corneal topography will be repeated after 5 minutes.
For all patients, the Barrett Universal II formula will be used for calculation of IOL power. Predicted refraction outcome will be referred to as SEQ. The chief surgeon will perform the uneventful standard cataract operation with in-the-bag implantation of a HOYA IOL (Model 251) through a 2.4-mm corneal incision.
A Subjective Refraction using plus principle will be performed one month after the operation, and ETDRS visual acuity charts will be used to measure best-corrected visual acuity. Refraction will be described as SR (postoperative SEQ) and will be calculated as:
SR = sphere + (0.5*cylinder)
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| sodium hyaluronate 0.1% | Active Comparator | First preoperative Biometry of the eye at the IOL Master® will be measured. Then, corneal topography will be measure at the Oculus pentacam®. Afterwards, sodium hyaluronate 0.1% will be installed and biometry and corneal topography will be repeated after 5 minutes. |
|
| sodium hyaluronate 0.3% | Active Comparator | First preoperative Biometry of the eye at the IOL Master® will be measured. Then,corneal topography will be measure at the Oculus pentacam®. Afterwards, sodium hyaluronate 0.3% will be installed and biometry and corneal topography will be repeated after 5 minutes. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| sodium hyaluronate 0.1% | Device | Instillation of one drop sodium hyaluronate 0.1% |
|
| Measure | Description | Time Frame |
|---|---|---|
| keratometric value of the eye measured with Master 500 before and after 5 minutes of installation of artificial tears (sodium hyaluronate 0.1% or 0.3% eye drops). | k-value (k, k1, k2 in Diopter) | 5 minutes |
| Axial length of the eye measured with Master 500 before and after 5 minutes of installation of artificial tears (sodium hyaluronate 0.1% or 0.3% eye drops). | Axial length (AL in mm) | 5 minutes |
| Anterior chamber depth of the eye measured with Master 500 before and after 5 minutes of installation of artificial tears (sodium hyaluronate 0.1% or 0.3% eye drops). | Anterior chamber depth (ACD in mm) | 5 minutes |
| Sim K of the eye measured with Oculus Pentacam before and after 5 minutes of installation of artificial tears (sodium hyaluronate 0.1% or 0.3% eye drops). | Sim K (k1, k2 in Diopter) | 5 minutes |
| Total Corneal Refractive Power of the eye measured with Oculus Pentacam before and after 5 minutes of installation of artificial tears (sodium hyaluronate 0.1% or 0.3% eye drops). | Total Corneal Refractive Power (TCRP in Diopter), | 5 minutes |
| Total Corneal Irregular Astigmatism of the eye measured with Oculus Pentacam before and after 5 minutes of installation of artificial tears (sodium hyaluronate 0.1% or 0.3% eye drops). | Total Corneal Irregular Astigmatism (TCIA in Diopter) | 5 minutes |
| Predicted spherical equivalent (SE) calculated with Barrett Universal II formula before and after 5 minutes of installation of artificial tears (sodium hyaluronate 0.1% or 0.3% eye drops). |
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Inclusion Criteria:
Exclusion Criteria:
• Abnormality of the cornea (scaring of the cornea)
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ling Bai, MD,PhD | Contact | 13571495415 | larkling@163.com |
| Name | Affiliation | Role |
|---|---|---|
| Ling Bai, MD,PhD | Second Affiliated Hospital of Xi'an Jiaotong University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Ophthalmology, Second affiliated hospital of Xian Jiaotong University | Recruiting | Xi'an | Shaanxi | 710004 | China |
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Corneal topography and Biometry will be performed in individuals with age-relate cataract. Patients will be classified as dry eye or normal eye based on BUT. The tear film breakup (BUT) time of less than 5 seconds will be diagnosed as dry eyes. One of two artificial tear eye drops will be instilled in the eye, and corneal topography and biometry will be repeated after 5 minutes of application
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| sodium hyaluronate 0.3% | Device | Instillation of one drop sodium hyaluronate 0.3% |
|
Predicted spherical equivalent (SEQ in Diopter) |
| 5 minutes |
| Postoperative spherical equivalent (SE) measured one month after surgery. | Postoperative spherical equivalent (SE in Diopters) | one month after surgery |
| ID | Term |
|---|---|
| D015352 | Dry Eye Syndromes |
| ID | Term |
|---|---|
| D007766 | Lacrimal Apparatus Diseases |
| D005128 | Eye Diseases |
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